/* jtoxkit.css - Styling for all jToxKit parts
*/
.jtox-panel,
.jtox-foldable {
	background: #eee; /* Old browsers */
	background: -moz-linear-gradient(top, rgba(255,255,255,.5) 0%, rgba(200,200,200,.5) 100%); /* FF3.6+ */
	background: -webkit-gradient(linear, left top, left bottom, color-stop(0%,rgba(255,255,255,.5)), color-stop(100%,rgba(200,200,200,.5))); /* Chrome,Safari4+ */
	background: -webkit-linear-gradient(top, rgba(255,255,255,.5) 0%,rgba(200,200,200,.5) 100%); /* Chrome10+,Safari5.1+ */
	background: -o-linear-gradient(top, rgba(255,255,255,.5) 0%,rgba(200,200,200,.5) 100%); /* Opera11.10+ */
	background: -ms-linear-gradient(top, rgba(255,255,255,.5) 0%,rgba(200,200,200,.5) 100%); /* IE10+ */
	background: linear-gradient(top, rgba(255,255,255,.5) 0%,rgba(200,200,200,.5) 100%); /* W3C */
  border: 1px solid #aaa;
  border-top: 1px solid #ccc;
  border-left: 1px solid #ccc;
  -moz-border-radius: 7px;
  -webkit-border-radius: 7px;
  border-radius: 7px;
  padding-top: 7px;
  padding-bottom: 3px;
}

.jtox-foldable:hover {
	background: #ddd; /* Old browsers */
	background: -moz-linear-gradient(top, rgba(255,255,255,.2) 0%, rgba(200,200,200,.2) 100%); /* FF3.6+ */
	background: -webkit-gradient(linear, left top, left bottom, color-stop(0%,rgba(255,255,255,.2)), color-stop(100%,rgba(200,200,200,.2))); /* Chrome,Safari4+ */
	background: -webkit-linear-gradient(top, rgba(255,255,255,.2) 0%,rgba(200,200,200,.2) 100%); /* Chrome10+,Safari5.1+ */
	background: -o-linear-gradient(top, rgba(255,255,255,.2) 0%,rgba(200,200,200,.2) 100%); /* Opera11.10+ */
	background: -ms-linear-gradient(top, rgba(255,255,255,.2) 0%,rgba(200,200,200,.2) 100%); /* IE10+ */
	background: linear-gradient(top, rgba(255,255,255,.2) 0%,rgba(200,200,200,.2) 100%); /* W3C */
}


.jtox-foldable {
  padding: 5px;
}

.jtox-foldable.folded>.content {
  display: none;
}

.jtox-foldable.folded>.title {
  background: url(../images/sort_desc.png) right top no-repeat;
}

.jtox-foldable>.title {
  background: url(../images/sort_asc.png) right top no-repeat;
  background-size: 19px 19px;
}

.jtox-fadable {
  -moz-transition: opacity ease 300ms;
  -ms-transition: opacity ease 300ms;
  -o-transition: opacity ease 300ms;
  -webkit-transition: opacity ease 300ms;
  transition: opacity ease 300ms;
}

.jtox-toolkit {
  clear: both;
}

.jtox-toolkit .jtox-details {
  font-size: 80%;
}

.jtox-toolkit sup.helper {
  opacity: 0.7;
}

.jtox-toolkit sup.helper span.ui-icon {
  vertical-align: top !important;
  display: inline-block;
}

.jtox-toolkit sup {
  font-size: smaller;
  vertical-align: super;
}

.jtox-toolkit sub {
  font-size: smaller;
  vertical-align: sub;
}

.jtox-toolkit sup a {
  text-decoration: none;
}

.jtox-template {
  display: none !important;
}

.jtox-toolkit .size-quarter {
  width: 25%;
}

.jtox-toolkit .size-third {
  width: 33%;
}

.jtox-toolkit .size-half {
  width: 50%;
}

.jtox-toolkit .size-full {
  width: 100%;
}

.jtox-toolkit .top {
  vertical-align: top !important;
}

.jtox-toolkit .middle {
  vertical-align: middle !important;
}

.jtox-toolkit .center {
  text-align: center !important;
}

.jtox-toolkit .right {
  text-align: right !important;
}

.jtox-toolkit .nomargin {
	margin: 0px !important;
}

.jtox-toolkit .font-small {
  font-size: small;
}

.jtox-toolkit .font-smaller {
  font-size: smaller;
}

.jtox-toolkit .font-big {
  font-size: large;
}

.jtox-toolkit .font-bigger {
  font-size: larger;
}

.jtox-toolkit .font-heavy {
  font-weight: bold;
}

.jtox-toolkit .transparent {
  opacity: 0.3;
}

.jtox-toolkit .paddingless {
  padding: 0px !important;
}

.jtox-toolkit .borderless {
  border:0px !important;
}

.jtox-toolkit .borderless-top,
.jtox-toolkit .borderless-top * {
  border-top: 0px !important;
}

.jtox-toolkit .borderless-bottom,
.jtox-toolkit .borderless-bottom * {
  border-bottom: 0px !important;
}

.cc-flex, cc-fixed {
  box-sizing: border-box;
  position: relative;
}

/* Make table helper elements, like paging, filter, etc. in one line...
*/
.jtox-toolkit .dataTables_filter label input,
.jtox-toolkit .dataTables_length label select,
.jtox-inline {
  display: inline-block;
}

.jtox-toolkit table.dataTable td,
.jtox-toolkit table.dataTable th {
  border:1px solid #ccc;
  overflow: hidden;
}

.jtox-toolkit .shortened {
  max-height: 25px;
  overflow: hidden;
  text-overflow: ellipsis;
  white-space: nowrap;
}

.jtox-toolkit .breakable {
  word-wrap: break-word;
  white-space: normal;
}

.jtox-toolkit .word-break {
  word-break: break-all;
}

.jtox-toolkit .non-breakable {
  word-break:normal;
  word-wrap: normal;
  white-space: nowrap;
}

.jtox-hidden {
  display: none !important;
}

.jtox-toolkit .float-right {
	float: right !important;
}

.jtox-toolkit span.units {
  font-size: 80%;
}

.jtox-diagram {
  position: relative;
}

.jtox-diagram img {
  border: 0px;
}

.jtox-toolkit a.select-all,
.jtox-toolkit a.unselect-all {
  text-decoration: underline;
}

.jtox-toolkit .loading {
  background: url(../images/waiting_small.gif) right top no-repeat;
  background-size: 16px 16px;
  min-width: 16px;
  min-height: 16px;
}

.jtox-toolkit button.loading,
.jtox-toolkit span.loading {
  background-position: center center;
  text-fill-color: rgba(0, 0, 0, 0);
  color: rgba(0, 0, 0, 0);
}

.jtox-toolkit input[type="password"],
.jtox-toolkit input[type="search"],
.jtox-toolkit input[type="text"],
textarea,
select {
  margin-bottom: 10px;
}

.jtox-toolkit input[type="password"].jt-inlineaction,
.jtox-toolkit input[type="search"].jt-inlineaction,
.jtox-toolkit input[type="text"].jt-inlineaction,
.jtox-toolkit select.jt-inlineaction {
  margin: 1px;
  box-sizing: border-box;
  width: 100%;
}

.jtox-toolkit input.jt-inlineaction {
  border: 0px;
  border-radius: 3px;
  background-color: transparent;
}

.jtox-toolkit input.jt-inlineaction:focus,
.jtox-toolkit input.jt-inlineaction:hover {
  border: inherit;
  margin: 0px;
}

.jtox-toolkit input.jt-inlineaction:focus {
  background-color: #fefefe;
}

.jtox-diagram span.ui-icon {
  position: absolute;
  bottom: 0px;
  right: 0px;
  display: none;
}

.jtox-diagram:hover span.ui-icon {
  display: block;
}

.jtox-toolkit a,
.jtox-toolkit a:visited,
.jtox-toolkit a:active {
  color: inherit;
}

img.jtox-smalldiagram {
  width: 125px;
  height: 125px;
}

.jtox-medium-box {
  margin: 2px;
  padding-left: 2px;
  padding-right: 2px;
  display: inline-block;
  min-width: 220px;
  height: auto;
  vertical-align: top;
}

.jtox-endpoint thead {
  display: none;
}

.jtox-toolkit .jtox-border-box {
  box-sizing: border-box;
  border: 1px solid #666;
  border-radius: 6px;
  padding: 10px;
  width: 100%;
  height: 100%;
}

.jtox-toolkit li.tagit-choice a.tagit-close {
  opacity: 0.4;
}

.jtox-toolkit li.tagit-choice.tag-value,
.jtox-toolkit li.tagit-choice.tag-unit {
  border: 0px;
  background: inherit;
  padding-right: 0px;
}

.jtox-toolkit li.tagit-choice.tag-value a.tagit-close,
.jtox-toolkit li.tagit-choice.tag-unit a.tagit-close {
  display: none;
}

.jtox-toolkit li.tagit-choice.tag-value {
  font-weight: bold;
}

.jtox-toolkit li.tagit-choice.tag-unit {
  font-size: 80%;
  line-height: 1.2rem;
}

button.jt-alert {
	display: inline-block;
	background: #a41515;
	color: #fff;
	text-shadow: 0px 1px 0px #4d4d4d;
}

button.jt-toggle {
  display: inline-block;
  border: 1px solid #aaa;
  border-radius: 5px;
  background: #eee;
  opacity: 0.7;
  width: 24px;
  text-align: center;
  vertical-align: middle;
  padding: 2px;
  font-weight: bold;
  margin: 0px;
}

button.jt-toggle:hover,
button.jt-toggle.active {
  background: #aaa;
  opacity: 1.0;
}

/* Start of multi-row table-related classes */
.jtox-toolkit table.dataTable td.jtox-multi {
  padding: 0px;
}

td.jtox-multi table {
  margin: 0px;
}

td.jtox-multi table td {
  border-left: 0px !important;
  border-right: 0px !important;
  border-bottom: 0px !important;
}

td.jtox-multi table tr:first-child td {
  border-top: 0px !important;
}

td.jtox-multi table {
  height: 100%;
  width: 100%;
}

.jtox-required:after {
  content: ' *';
}
/* toxtstudy.css - Styling for toxstudy engine
*/

.jtox-search input[type="text"] {
  min-width: 380px;
  height: 20px;
  -moz-transition: width 0.3s ease-out;
  -webkit-transition: width 0.3s ease-out;
  transition: width 0.3s ease-out;
  margin-bottom: 0px;
}

.jtox-search label {
  display: inline-block;
  font-weight: normal;
  font-size: 1rem;
}

#searchcontext input {
  height: auto;
  width: 99%;
  box-sizing: border-box;
}

.jtox-search .search-pane .jtox-inline input,
.jtox-search .search-pane .jtox-inline select {
  font-size: 1.1em;
  margin-top: 2px;
  display: inline-block;
  vertical-align: baseline;
}

.jtox-search .search-pane .jtox-inline select {
  margin: 6px;
  height: 26px;
}

.jtox-search form {
  margin: 0px;
}

.jtox-search form>div {
  margin: 2px 4px 4px 4px;
  box-sizing: border-box;
}

.jtox-search form div.jq-buttonset {
  margin-top: 6px;
}

.jtox-search .search-pane button {
  vertical-align: top;
  margin-bottom: 0px;
}

.jtox-search .searchsimilarity select {
  width: 5em;
}

.jtox-search .searchauto.dynamic>div {
  white-space: nowrap;
  padding-top: 10px;
}

.jtox-search .search-pane div.dynamic {
  min-height: 40px;
  float: left;
}

.jtox-search .search-pane .dynamic.hidden {
  display: none;
}

.jtox-search .ketcher {
  display: block;
  height: auto;
  position: relative;
  left: 0px;
  -moz-transition: all 0.5s ease, opacity 0.2s;
  -webkit-transition: all 0.5s ease, opacity 0.2s;
  transition: all 0.5s ease, opacity 0.2s;
}

.jtox-search .ketcher.shrinken {
  left: 100%;
/*   opacity: 0.0; */
}

.jtox-search .ketcher .toolEmptyCell {
  vertical-align: middle;
}

.jtox-search .ketcher .toolEmptyCell button {
  margin: 0px;
  padding: 4px 8px;
}

.jtox-search .ketcher .toolEmptyCell button span {
  display: inline-block;
}
/* toxtcompound.css - Styling for tox-compound engine
*/

.jtox-ds-fixed,
.jtox-ds-variable {
  border: 0px;
  padding: 0px;
  margin: 0px;
  vertical-align: top;
  overflow-x: scroll;
  overflow-y: hidden;
}

.jtox-ds-fixed {
  display: inline-block;
  width: 450px;
  float: left;
  overflow-x: hidden;
}

.jtox-ds-feature {
  display: inline-block;
  width: 250px;
  border: 0px;
  padding: 0px;
  margin: 2px 15px 2px 2px;
  text-overflow: ellipsis;
  overflow: hidden;
}

.jtox-selection {
  font-size: 80%;
  float: right;
  vertical-align: top;
}

.jtox-ds-tables {
  position: relative;
}

.jtox-ds-tables .jt-processing,
.jtox-ds-tables .jt-error {
  text-align: center;
  display: none;
}

.jtox-ds-tables .jt-processing .message {
  background: url("../images/waiting_big.gif") left center no-repeat;
  background-size: 30px 30px;
  width: auto;
  min-height: 30px;
  padding-left: 35px;
  padding-top: 8px;
  overflow: visible;
  display: inline-block;
}

.jtox-ds-tables .jt-error .message {
  color: red;
}

.jtox-ds-tables .jtox-details-box {
  position: absolute;
  margin: 0px;
  left: 0px;
  top: 0px;
  padding: 0px;
  z-index: 10;
  height: auto;
}

.jtox-ds-tables .jtox-inline,
.jtox-ds-tables td {
  vertical-align: top;
}

.jtox-ds-tables td .shortened {
  max-width: 75px;
}

.jtox-ds-export {
  float: right !important;
}

.jtox-ds-download {
  padding:0px 5px 0px 5px;
}

.jtox-ds-details * {
  font-size: small;
}

.jtox-ds-details .ui-tabs {
  padding: 0px;
  border: 0px;
  margin: 0px;
}

div.jtox-details-table {
  padding: 12px 0px 0px 0px !important;
}

.jtox-details-table table {
  width: 100%;
  height: auto;
  vertical-align: baseline;
}

.jtox-controls {
  padding: 10px;
  vertical-align: baseline;
}

.jtox-controls .paginate_disabled_previous,
.jtox-controls .paginate_enabled_previous,
.jtox-controls .paginate_disabled_next,
.jtox-controls .paginate_enabled_next {
  float: none;
}

.jtox-controls select {
  width: 75px;
}

.jtox-controls select,
.jtox-controls input {
  display: inline-block;
  font-size: 1.1em;
}

.jtox-controls input {
  position: absolute;
  right:10px;
  width: 25%;
}

.jtox-controls span.high {
  font-weight: bold;
  font-size: 1.1em;
}
.jtox-substance table td div.shortened {
  width: 120px;
}
.jtox-toolkit table.composition-info.dataTable td,
.jtox-toolkit table.composition-info.dataTable th {
  border: 0px;
  padding-bottom: 0px;
  padding-top: 0px;
}

.jtox-toolkit table.composition-info.dataTable th {
  width: 20%;
  text-align: right;
}

.jtox-toolkit table.composition-table td {
  vertical-align: top;
}
/* toxtstudy.css - Styling for toxstudy engine
*/

div.jtox-study,
div.jtox-compo-tab,
div.jtox-substance {
  display: block;
  font-size: small;
  border-radius: 5px;
  padding: 5px 5px 35px 5px;
}

.jtox-compo-tab {
  margin-top: 25px;
  margin-bottom: 45px;  
}

div.jtox-study-tab.unloaded  {
  background: url(../images/waiting_big.gif) center center no-repeat;
  background-size: 30px 30px;
}

div.jtox-study-tab.unloaded div.jtox-study {
  display: none;
}

div.jtox-study.folded {
  padding-bottom: 5px;
}

div.jtox-study .title {
  font-weight: bold;
  clear: both;
  padding: 0px;
  margin: 0px;
  border: 0px;
  width: 100%;
}

div.jtox-foldable.jtox-study.unloaded>.title {
  background: url(../images/waiting_small.png) right top no-repeat;
  background-size: 16px 16px;
}

div.jtox-study-tab.ui-tabs-panel {
  padding-left: 0px;
  padding-bottom: 0px;
  padding-right: 0px;
  width: 100%;
  height: 100%;
}

div.jtox-study-tab div button {
	font-size: 80%;
	padding:4px 8px 4px 8px;
}

div.jtox-study-tab .dataTables_wrapper {
  overflow: hidden;  
  width: 100%;
}

.jtox-toolkit .jtox-study table td {
  word-wrap: break-word;
}
/* jToxLog styling
*/

.jtox-log {
  position: fixed;
	height: 144px;
  width: 99%;
  right: 0px;
	bottom: 0px;
	z-index: 100;
	transition: bottom 0.5s ease;
	-moz-transition: bottom 0.5s ease;
	-webkit-transition: bottom 0.5s ease;
	-o-transition: bottom 0.5s ease;
	box-shadow: -3px 7px 7px #999; 
}

.jtox-log.right-side {
  position: fixed;
	height: 144px;
  width: 95%;
  right: 5px;
	bottom: 0px;
	z-index: 100;
	transition: bottom 0.5s ease;
	-moz-transition: bottom 0.5s ease;
	-webkit-transition: bottom 0.5s ease;
	-o-transition: bottom 0.5s ease;
	box-shadow: 7px 7px 7px #999;  
}

.jtox-log.hidden {
  bottom: -120px;
}

.jtox-log div.icon {
  display: inline-block;
  vertical-align: middle;
  color: rgba(0, 0, 0, 0);
  width: 16px;
  height: 16px;
}

.jtox-log .status {
  background: #fff;
  position: absolute;
  top: 1px;
  width: 32px;
  height: 24px;
  text-align: center;
  border-top-right-radius: 5px;
  border-top-left-radius: 5px;
  border-left: 1px solid black;
  border-top: 1px solid black;
  border-right: 1px solid black;
  border-bottom: 0px;
}

.jtox-log .jt-faded {
  opacity: 0.2;
}

.jtox-log .list-wrap {
  background: #fff;
  position: absolute;
  box-sizing: border-box;
  top: 0px;
  width: 100%;
  border: 1px solid black;
  border-radius: 5px;
  border-top-left-radius: 0px;
  min-height: 50px;
  height: 100%;
  overflow: scroll;
  margin-top: 25px;
  padding-left: 8px;
}

.jtox-log.right-side .list-wrap {
  border-top-right-radius: 0px;
  border-top-left-radius: 5px;
}

.jtox-log .list-root {
  margin-bottom: 24px;
  margin-right: 8px;
}

.jtox-log .logline {
  margin-top: 2px;
  background: inherit;
  border: 0px;
  font-style: italic;
  font-size: 90%;
  overflow: hidden;

  -moz-transition: height ease 300ms;
  -ms-transition: height ease 300ms;
  -o-transition: height ease 300ms;
  -webkit-transition: height ease 300ms;
  transition: height ease 300ms;
}

.jtox-log .logline .content {
  vertical-align: middle;
}

.jtox-log .logline .details {
  margin-left: 18px;
  vertical-align: top;
}