E.ANIMAL_MODEL
has-value: rat

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 0.14

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 25.0

concentration
has-value: 0 ug/ml

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

material
has-value: In Vitro stimulation

NM100_CA_TK6_3hr_8
publisher: CBT

SIZE_MEASUREMENT_TYPE
has-value: shape

ANALYSIS_ALGORITHM

material
has-value: In Vitro stimulation

SIZE_MEASUREMENT_TYPE
has-value: size distribution

BATCH_DISPERSION_SIZE_DISTRIBUTION
type: BAO_0000179
STATO_0000035: 0.0 ± 0.0
has-unit: nm

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 0.42

NM100_AB_A549_3h_6
publisher: NILU

Batch Dispersion Quality
type: OBI_0000272

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 0.0

HYDRODYNAMIC_DIAMETER
type: BAO_0000179
STATO_0000035: 224.51 ± 0.17
has-unit: nm

SIZE
type: CHMO_0002119
type: BAO_0000015
source: NM100RPMI100/24
BAO_0002846: DLS

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

NM100_CA_TK6_3hr_11
publisher: CBT

GENOTOXICITY
type: BAO_0002167
type: BAO_0000015
source: NM100_CA_A549_3h_7
BAO_0002846: DNA Strand breaks

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 9.65

SIZE_MEASUREMENT
has-value: Z-ave hydrodynamic diameter

FERET_MINIMAL_DIAMETER
type: BAO_0000179
STATO_0000035: 130.3 ± 14.1
has-unit: nm

nominal diameter & length
type: CHMO_0002119
type: BAO_0000015
source: Provided
BAO_0002846: NANoREG supplier

concentration
has-value: 0 ug/ml

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 0.42

T.INSTRUMENT_MODEL
has-value: Batch Dispersion Quality

T.INSTRUMENT_MODEL
has-value: TEM

GENDER
has-value: Male

Batch Dispersion Quality
type: OBI_0000272

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 1.41

material
has-value: In Vitro stimulation

material
has-value: In Vitro stimulation

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 104.0 ± 6.427
has-unit: %

T.INSTRUMENT_MODEL
has-value: TEM

SIZE_MEASUREMENT_TYPE
has-value: size distribution

T.INSTRUMENT_MODEL
has-value: TEM

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 4.24

PERCENTAGE_VIABILITY_COMPARED_TO_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-unit: %
has-value: 47.983464

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 1.0

T.INSTRUMENT_MODEL
has-value: TEM

material
has-value: In Vitro stimulation

GLOBAL_MEAN_SIZE
type: BAO_0000179
STATO_0000035: 310.2 ± 110.0
has-unit: nm

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

PERCENTAGE_VIABILITY_COMPARED_TO_CONTROL
type: BAO_0000179
has-unit: % DNA in Tail
has-value: 5.66

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 17.64 ± 1.758
has-unit: %

T.INSTRUMENT_MODEL
has-value: Batch Dispersion Quality

SIZE_MEASUREMENT
has-value: Median Feret Minimal Diameter

DLS
type: OBI_0000272

SIZE_MEASUREMENT
has-value: Mode Feret Minimal Diameter

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 5.597

SIZE_MEASUREMENT
has-value: Z-ave hydrodynamic diameter

material
has-value: In Vitro stimulation

DNA Strand breaks
type: OBI_0000272

T.INSTRUMENT_MODEL
has-value: TEM

SIZE_MEASUREMENT_TYPE
has-value: shape

T.INSTRUMENT_MODEL
has-value: TEM

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 88.0 ± 0.064
has-unit: %

ILC phase 3 - Inmetro_pp
publisher: INMETRO

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 6.631 ± 1.333
has-unit: %

SIZE_MEASUREMENT_TYPE
has-value: intensity-weighted size distribution

concentration
has-value: 0 ug/ml

BATCH_DISPERSION_SIZE_DISTRIBUTION
type: BAO_0000179
STATO_0000035: 942.9 ± 1988.0
has-unit: nm

material
has-value: Positive control

FERET_MINIMAL_DIAMETER
type: BAO_0000179
STATO_0000035: 113.2 ± 24.7
has-unit: nm

ECD
type: BAO_0000179
STATO_0000035: 125.0 ± 4.0
has-unit: nm

material
has-value: none

CONCENTRATION
has-unit: ug/cm2
has-value: 30.0

NO_CONCENTRATION
type: BAO_0000179
has-condition: CONCENTRATION
STATO_0000035: 2.497 ± 0.33
has-unit: uM(10^-6 mol)/L

UNITO_LDH_NM100_THP_24H
publisher: CNR

material
has-value: In Vitro stimulation

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 0.0

DNA Strand breaks
type: OBI_0000272

TEST_TYPE
has-value: automatic count

SIZE_MEASUREMENT
has-value: global mean size

ILC phase 3 - Inmetro_Agg
publisher: INMETRO

material
has-value: In Vitro stimulation

material
has-value: none

SIZE_MEASUREMENT
has-value: Z-ave hydrodynamic diameter

material
has-value: In Vitro stimulation

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 1.41

T.INSTRUMENT_MODEL
has-value: TEM

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 1.41

VIABILITY
type: ENM_0000068
type: BAO_0000015
source: NM100_AB_A549_24h_7
BAO_0002846: Alamar Blue

ECD
type: BAO_0000179
STATO_0000035: 105.0 ± 2.0
has-unit: nm

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

SIZE_MEASUREMENT
has-value: Median Roundness

DISPERSION QUALITY
type: CHMO_0002119
type: BAO_0000015
source: Benchmarking_JRCNM01000a_TEK_2
BAO_0002846: Batch Dispersion Quality

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 7.256

T.INSTRUMENT_MODEL
has-value: TEM

T.INSTRUMENT_MODEL
has-value: TEM

SIZE_MEASUREMENT
has-value: Mean ECD

material
has-value: none

NO_CONCENTRATION
type: BAO_0000179
has-condition: POSITIVE_CONTROL_CONCENTRATION
has-condition: CONCENTRATION
STATO_0000035: 245.578 ± 35.176
has-unit: uM(10^-6 mol)/L

material
has-value: Negative control

HYDRODYNAMIC_DIAMETER
type: BAO_0000179
STATO_0000035: 245.9 ± 2.7
has-unit: nm

material
has-value: none

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 5.497

SIZE_MEASUREMENT_TYPE
has-value: size distribution

TOTAL_NUMBER_OF_CELLS_IN_BAL
type: BAO_0000179
has-condition: DOSE
STATO_0000035: 6450000.0 ± 1170000.0

SIZE_MEASUREMENT
has-value: Mode ECD

FERET_MINIMAL_DIAMETER
type: BAO_0000179
STATO_0000035: 136.0 ± 13.5
has-unit: nm

material
has-value: In Vitro stimulation

DIAMETER
type: BAO_0000179
STATO_0000035: 50.0-150.0
has-unit: nm
has-value: 50-150 nm

T.INSTRUMENT_MODEL
has-value: TEM

ROUNDNESS
type: BAO_0000179
STATO_0000035: 0.8 ± 0.02

SIZE_MEASUREMENT_TYPE
has-value: intensity-weighted size distribution

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 12.366

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 4.24

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

SIZE
type: CHMO_0002119
type: BAO_0000015
source: NM100_CA_TK6_5
BAO_0002846: DLS

material
has-value: In Vitro stimulation

material
has-value: In Vitro stimulation

SPECIFIC_SURFACE_AREA
type: BAO_0000179
has-unit: m2/g
has-value: 9
has-value: 9.0

ROUNDNESS
type: BAO_0000179
STATO_0000035: 0.75 ± 0.17

material
has-value: none

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 14.14

T.INSTRUMENT_MODEL
has-value: TEM

SIZE_MEASUREMENT_TYPE
has-value: shape

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

CONCENTRATION
has-unit: ug/cm2
has-value: 0.3

ECD
type: BAO_0000179
STATO_0000035: 107.0 ± 3.0
has-unit: nm

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 69.15 ± 14.681
has-unit: %

SIZE
type: CHMO_0002119
type: BAO_0000015
source: ILC_Phase3_CODA_PP
BAO_0002846: TEM

PERCENTAGE_VIABILITY_COMPARED_TO_CONTROL
type: BAO_0000179
has-unit: % DNA in Tail
has-value: 6.568

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

ECD
type: BAO_0000179
STATO_0000035: 127.5 ± 40.9
has-unit: nm

PERCENTAGE_VIABILITY_COMPARED_TO_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-unit: %
has-value: 8.01

material
has-value: none

SIZE_MEASUREMENT
has-value: Mode Aspect Ratio

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 1.41

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 96.0 ± 5.662
has-unit: %

T.INSTRUMENT_MODEL
has-value: TEM

FERET_MINIMAL_DIAMETER
type: BAO_0000179
STATO_0000035: 204.0 ± 32.8
has-unit: nm

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 101.0 ± 5.296
has-unit: %

material
has-value: In Vitro stimulation

Polymorphism
type: NPO 1512
type: BAO_0000015
source: Provided
BAO_0002846: NANoREG supplier

SIZE_MEASUREMENT
has-value: Median ECD

T.INSTRUMENT_MODEL
has-value: TEM

concentration
has-value: 0 ug/ml

material
has-value: none

T.INSTRUMENT_MODEL
has-value: TEM

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 29.19

SPECIFIC_SURFACE_AREA
type: BAO_0000179
has-unit: m2/g
has-value: 9
has-value: 9.0

NM100_CA_TK6_8
publisher: CBT

ANALYSIS_ALGORITHM

material
has-value: none

T.INSTRUMENT_MODEL
has-value: TEM

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 4.24

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 25.748

ORGANIC_COAT./ASS._ORGANICS
type: BAO_0000179
has-value: no

ANALYSIS_ALGORITHM

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 16.402 ± 2.162
has-unit: %

SIZE_MEASUREMENT_TYPE
has-value: shape

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 24.018 ± 6.8
has-unit: %

ASPECT_RATIO_D1_D3
type: BAO_0000179
STATO_0000035: 0.77 ± 0.02

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 4.424

SIZE_MEASUREMENT_TYPE
has-value: size distribution

ECD
type: BAO_0000179
STATO_0000035: 97.0 ± 3.0
has-unit: nm

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 42.41

concentration
has-value: 0 ug/ml

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

material
has-value: Negative control

BATCH_DISPERSION_SIZE_DISTRIBUTION
type: BAO_0000179
STATO_0000035: 0.0 ± 0.0
has-unit: nm

ANALYSIS_ALGORITHM

material
has-value: none

SIZE_MEASUREMENT_TYPE
has-value: size distribution

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 141.37

LDH
type: OBI_0000272

SIZE_MEASUREMENT
has-value: Batch dispersion size distribution

ECD
type: BAO_0000179
STATO_0000035: 139.0 ± 2.0
has-unit: nm

material
has-value: none

T.INSTRUMENT_MODEL
has-value: TEM

NO_CONCENTRATION
type: BAO_0000179
has-condition: CONCENTRATION
STATO_0000035: 1.929 ± 0.172
has-unit: uM(10^-6 mol)/L

GENDER
has-value: Male

Benchmarking_JRCNM01000a_TEK_2
publisher: TEKNIKER

T.INSTRUMENT_MODEL
has-value: Batch Dispersion Quality

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 22.124

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 0.14

material
has-value: In Vitro stimulation

material
has-value: Negative control

material
has-value: In Vitro stimulation

T.INSTRUMENT_MODEL
has-value: TEM

SIZE_MEASUREMENT
has-value: Mode Solidity

T.INSTRUMENT_MODEL
has-value: TEM

HYDRODYNAMIC_DIAMETER
type: BAO_0000179
STATO_0000035: 213.56 ± 0.18
has-unit: nm

LDH
type: OBI_0000272

SIZE_MEASUREMENT
has-value: Batch dispersion size distribution

UNITO_LDH_NM100_RAW_48H
publisher: CNR

material
has-value: In Vitro stimulation

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 67.3 ± 2.749
has-unit: %

SIZE_MEASUREMENT
has-value: Mean ECD

SIZE_MEASUREMENT
has-value: Median Feret Minimal Diameter

ASPECT_RATIO_D1_D3
type: BAO_0000179
STATO_0000035: 0.89 ± 0.11

SIZE_MEASUREMENT_TYPE
has-value: size distribution

GENOTOXICITY
type: BAO_0002167
type: BAO_0000015
source: NM100_CA_TK6_3hr_11
BAO_0000209: NRTR-00000000-0000-0000-0000-000000001166
BAO_0002846: DNA Strand breaks

material
has-value: Positive control

material
has-value: none

CONCENTRATION
has-unit: ug/cm2
has-value: 3.0

GENOTOXICITY
type: BAO_0002167
type: BAO_0000015
source: NM100_CA_A549_24h_6
BAO_0002846: DNA Strand breaks

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 42.41

TEST_TYPE
has-value: automatic count

material
has-value: In Vitro stimulation

ECD
type: BAO_0000179
STATO_0000035: 79.5 ± 4.0
has-unit: nm

SIZE_MEASUREMENT
has-value: Mean Feret Minimal Diameter

material
has-value: none

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 68.68 ± 0.067
has-unit: %

SIZE_MEASUREMENT_TYPE
has-value: size distribution

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 0.14

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 0.14

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 100.0

BATCH_DISPERSION_SIZE_DISTRIBUTION
type: BAO_0000179
STATO_0000035: 292.7 ± 8.922
has-unit: nm

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

SIZE_MEASUREMENT
has-value: Mean Circularity

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 12.859

T.INSTRUMENT_MODEL
has-value: Batch Dispersion Quality

material
has-value: Negative control

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 100.0

material
has-value: none

SIZE_MEASUREMENT
has-value: Median ECD

material
has-value: In Vitro stimulation

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 0.42

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 98.0 ± 1.803
has-unit: %

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 18.126

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

HYDRODYNAMIC_DIAMETER
type: BAO_0000179
STATO_0000035: 240.5 ± 2.64
has-unit: nm

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 1.41

material
has-value: In Vitro stimulation

CONCENTRATION
has-unit: ug/cm2
has-value: 3.0

material
has-value: none

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 21.924 ± 3.026
has-unit: %

PERCENTAGE_VIABILITY_COMPARED_TO_CONTROL
type: BAO_0000179
has-unit: % DNA in Tail
has-value: 2.203

T.INSTRUMENT_MODEL
has-value: TEM

T.INSTRUMENT_MODEL
has-value: TEM

SIZE_MEASUREMENT_TYPE
has-value: shape

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 16.806

T.INSTRUMENT_MODEL
has-value: DLS

DISPERSION QUALITY
type: CHMO_0002119
type: BAO_0000015
source: ECOTOX_Dispersion_SINTEF_NM100
BAO_0002846: Batch Dispersion Quality

CONCENTRATION
has-unit: ug/cm2
has-value: 30.0

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 104.98 ± 9.034
has-unit: %

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 74.81 ± 10.759
has-unit: %

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 8.219 ± 0.954
has-unit: %

SIZE
type: CHMO_0002119
type: BAO_0000015
source: ILC phase 3 - Inmetro_pp
BAO_0000209: NRDM-00000000-0000-0000-0000-000000001766
BAO_0002846: TEM

NM-100 TiO2 50-150 nm
type: CHEBI_59999
label: JRCNM01000a
BFO_0000056: NRDM-00000000-0000-0000-0000-000000001766
BFO_0000056: NRTR-00000000-0000-0000-0000-000000001163
BFO_0000056: NRTR-00000000-0000-0000-0000-000000001165
BFO_0000056: NRTR-00000000-0000-0000-0000-000000001168
BFO_0000056: NRTR-00000000-0000-0000-0000-000000001164
BFO_0000056: NRTR-00000000-0000-0000-0000-000000001169
BFO_0000056: NRDM-00000000-0000-0000-0000-000000001778
BFO_0000056: NRTR-00000000-0000-0000-0000-000000001166
BFO_0000056: NRDM-00000000-0000-0000-0000-000000001765
BFO_0000056: NRTR-00000000-0000-0000-0000-000000001162

SOLIDITY
type: BAO_0000179
STATO_0000035: 0.97 ± 0.0

CONCENTRATION
has-unit: ug/cm2
has-value: 30.0

SIZE_MEASUREMENT
has-value: global mean size

ECD
type: BAO_0000179
STATO_0000035: 124.0 ± 4.0
has-unit: nm

SIZE
type: CHMO_0002119
type: BAO_0000015
source: JRCNM01000a_Agg
BAO_0002846: TEM

DNA Strand breaks
type: OBI_0000272

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

NO_CONCENTRATION
type: BAO_0000179
has-condition: CONCENTRATION
STATO_0000035: 2.237 ± 0.093
has-unit: uM(10^-6 mol)/L

T.INSTRUMENT_MODEL
has-value: DLS

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 92.0 ± 5.046
has-unit: %

material
has-value: none

SIZE_MEASUREMENT
has-value: Median Aspect Ratio

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 0.14

T.INSTRUMENT_MODEL
has-value: DLS

material
has-value: none

DNA Strand breaks
type: OBI_0000272

FERET_MINIMAL_DIAMETER
type: BAO_0000179
STATO_0000035: 104.0 ± 3.0
has-unit: nm

material
has-value: In Vitro stimulation

T.INSTRUMENT_MODEL
has-value: TEM

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 14.18

T.INSTRUMENT_MODEL
has-value: TEM

material
has-value: none

BATCH_DISPERSION_SIZE_DISTRIBUTION
type: BAO_0000179
STATO_0000035: 244.7 ± 2.8
has-unit: nm

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 6.045

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 0.42

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 89.0 ± 11.12
has-unit: %

T.INSTRUMENT_MODEL
has-value: TEM

ECD
type: BAO_0000179
STATO_0000035: 146.2 ± 7.5
has-unit: nm

NM100_CA-Fpg_TK6_24hr_11
publisher: CBT

ANALYSIS_ALGORITHM

TEM
type: OBI_0000272

ROUNDNESS
type: BAO_0000179
STATO_0000035: 0.83 ± 0.02

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 25.748

SIZE_MEASUREMENT_TYPE
has-value: shape

DISPERSION QUALITY
type: CHMO_0002119
type: BAO_0000015
source: NANOGENOTOX_Dispersion_SINTEF_NM100
BAO_0002846: Batch Dispersion Quality

material
has-value: In Vitro stimulation

SOLIDITY
type: BAO_0000179
STATO_0000035: 0.91 ± 0.03

material
has-value: Negative control

ANALYSIS_ALGORITHM

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 29.19

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 14.14

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 98.0 ± 7.967
has-unit: %

NO production
type: OBI_0000272

material
has-value: In Vitro stimulation

https://apps.ideaconsult.net/nanoreg1/owner/NNRG-04022171-cf37-b07b-b933-a6b8d57883ed
type: Dataset
publisher: NANoREG

FERET_MINIMAL_DIAMETER
type: BAO_0000179
STATO_0000035: 94.0 ± 4.0
has-unit: nm

ECD
type: BAO_0000179
STATO_0000035: 96.4 ± 34.2
has-unit: nm

SIZE_MEASUREMENT
has-value: Batch dispersion size distribution

T.INSTRUMENT_MODEL
has-value: TEM

DOSE
has-unit: mg/kg
has-value: 1.67

Batch Dispersion Quality
type: OBI_0000272

material
has-value: In Vitro stimulation

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 42.41

material
has-value: Negative control

T.INSTRUMENT_MODEL
has-value: TEM

SIZE_MEASUREMENT
has-value: Median Solidity

SIZE_MEASUREMENT
has-value: Z-ave hydrodynamic diameter

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 50.0

SIZE_MEASUREMENT
has-value: Batch dispersion size distribution

material
has-value: In Vitro stimulation

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 3.946

IMMUNOTOXICITY
type: NPO 1339
type: BAO_0000015
source: UNITO_NO_NM100_RAW_24H
BAO_0002846: NO production

SIZE_MEASUREMENT
has-value: Mode Feret Minimal Diameter

SIZE_MEASUREMENT
has-value: Mean ECD

SIZE_MEASUREMENT_TYPE
has-value: size distribution

NO_CONCENTRATION
type: BAO_0000179
has-condition: CONCENTRATION
STATO_0000035: 1.753 ± 0.337
has-unit: uM(10^-6 mol)/L

SIZE_MEASUREMENT_TYPE
has-value: size distribution

CONCENTRATION
has-unit: ug/cm2
has-value: 0.3

SIZE_MEASUREMENT_TYPE
has-value: size distribution

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 26.029 ± 0.064
has-unit: %

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 27.878 ± 13.089
has-unit: %

CIRCULARITY
type: BAO_0000179
STATO_0000035: 0.82 ± 0.02

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 4.24

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 8.519

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 0.0

ECD
type: BAO_0000179
STATO_0000035: 95.0 ± 3.0
has-unit: nm

material
has-value: In Vitro stimulation

SIZE_MEASUREMENT_TYPE
has-value: shape

material
has-value: In Vitro stimulation

SIZE_MEASUREMENT
has-value: Mode ECD

TEM
type: OBI_0000272

DLS
type: OBI_0000272

SIZE_MEASUREMENT_TYPE
has-value: size distribution

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 14.14

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 25.0

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

SIZE_MEASUREMENT
has-value: Mode Aspect Ratio

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

T.INSTRUMENT_MODEL
has-value: Batch Dispersion Quality

SIZE_MEASUREMENT
has-value: Mode ECD

SIZE_MEASUREMENT
has-value: Z-ave hydrodynamic diameter

FERET_MINIMAL_DIAMETER
type: BAO_0000179
STATO_0000035: 130.0 ± 3.0
has-unit: nm

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 141.37

PERCENTAGE_VIABILITY_COMPARED_TO_CONTROL
type: BAO_0000179
has-unit: % DNA in Tail
has-value: 15.15

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 25.0

material
has-value: none

FERET_MINIMAL_DIAMETER
type: BAO_0000179
STATO_0000035: 101.2 ± 4.6
has-unit: nm

SIZE_MEASUREMENT
has-value: Mean Feret Minimal Diameter

material
has-value: In Vitro stimulation

NM100_AB_A549_3h_7
publisher: NILU

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 42.41

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 38.543

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 70.69

INORGANIC_COAT./ASS._ELEMENTS
type: BAO_0000179
has-value: Fe,Si,Al

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 50.0

ECD
type: BAO_0000179
STATO_0000035: 221.3 ± 33.7
has-unit: nm

T.INSTRUMENT_MODEL
has-value: TEM

VIABILITY
type: ENM_0000068
type: BAO_0000015
source: UNITO_LDH_NM100_THP_24H
BAO_0002846: LDH

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 103.0 ± 2.02
has-unit: %

T.INSTRUMENT_MODEL
has-value: Batch Dispersion Quality

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 18.502

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 0.14

CONCENTRATION
has-unit: ug/cm2
has-value: 0.3

material
has-value: In Vitro stimulation

SIZE_MEASUREMENT_TYPE
has-value: shape

https://apps.ideaconsult.net/nanoreg1/interpretation/NRCR-d54636b3-3845-0e9e-2a40-1c9a3910653d
has-value: anatase

HYDRODYNAMIC_DIAMETER
type: BAO_0000179
STATO_0000035: 213.56 ± 0.18
has-unit: nm

T.INSTRUMENT_MODEL
has-value: TEM

T.INSTRUMENT_MODEL
has-value: TEM

DNA Strand breaks
type: OBI_0000272

PURITY_OF_PARTICLES
type: BAO_0000179
has-unit: wt%
has-value: 2.3

CONCENTRATION
has-unit: ug/cm2
has-value: 3.0

CIRCULARITY
type: BAO_0000179
STATO_0000035: 0.66 ± 0.09

JRCNM01000a_PP
publisher: INL

POSITIVE_CONTROL_CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 1.0

material
has-value: In Vitro stimulation

GENOTOXICITY
type: BAO_0002167
type: BAO_0000015
source: NM100_CA-Fpg_TK6_3hr_11
BAO_0000209: NRTR-00000000-0000-0000-0000-000000001168
BAO_0002846: DNA Strand breaks

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

SIZE_MEASUREMENT_TYPE
has-value: size distribution

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 90.07 ± 11.251
has-unit: %

DISPERSION QUALITY
type: CHMO_0002119
type: BAO_0000015
source: Benchmarking_JRCNM01000a_TEK_3
BAO_0002846: Batch Dispersion Quality

DNA Strand breaks
type: OBI_0000272

material
has-value: In Vitro stimulation

material
has-value: none

Chemical composition of particles
type: ENM_0000090
type: BAO_0000015
source: Provided
BAO_0002846: NANoREG supplier

SIZE_MEASUREMENT
has-value: Mean Solidity

ECD
type: BAO_0000179
STATO_0000035: 70.2 ± 2.3
has-unit: nm

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 42.41

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 100.0

T.INSTRUMENT_MODEL
has-value: TEM

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 42.41

material
has-value: none

VIABILITY
type: ENM_0000068
type: BAO_0000015
source: UNITO_LDH_NM100_THP_48H
BAO_0002846: LDH

material
has-value: In Vitro stimulation

BATCH_DISPERSION_SIZE_DISTRIBUTION
type: BAO_0000179
STATO_0000035: 0.0 ± 0.0
has-unit: nm

T.INSTRUMENT_MODEL
has-value: TEM

SIZE_MEASUREMENT
has-value: Mean Feret Minimal Diameter

material
has-value: none

LDH
type: OBI_0000272

SIZE_MEASUREMENT
has-value: Mode Feret Minimal Diameter

T.INSTRUMENT_MODEL
has-value: TEM

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 117.0 ± 1.315
has-unit: %

SIZE_MEASUREMENT_TYPE
has-value: shape

ANALYSIS_ALGORITHM

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 16.712

material
has-value: In Vitro stimulation

material
has-value: none

HYDRODYNAMIC_DIAMETER
type: BAO_0000179
STATO_0000035: 238.3 ± 3.03
has-unit: nm

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 0.14

BATCH_DISPERSION_SIZE_DISTRIBUTION
type: BAO_0000179
STATO_0000035: 240.1 ± 1.5
has-unit: nm

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 28.808 ± 2.746
has-unit: %

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 21.184

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 88.81 ± 13.044
has-unit: %

CONCENTRATION
has-unit: ug/cm2
has-value: 10.0

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 11.454 ± 1.382
has-unit: %

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 1.41

SOLIDITY
type: BAO_0000179
STATO_0000035: 0.97 ± 0.0

T.INSTRUMENT_MODEL
has-value: DLS

NANoREG supplier
type: OBI_0000272

FERET_MINIMAL_DIAMETER
type: BAO_0000179
STATO_0000035: 125.0 ± 4.0
has-unit: nm

SIZE
type: CHMO_0002119
type: BAO_0000015
source: JRCNM01000a
BAO_0002846: TEM

material
has-value: In Vitro stimulation

GENOTOXICITY
type: BAO_0002167
type: BAO_0000015
source: NM100_CA_TK6_3hr_8
BAO_0000209: NRTR-00000000-0000-0000-0000-000000001163
BAO_0002846: DNA Strand breaks

SIZE_MEASUREMENT
has-value: Batch dispersion size distribution

SIZE_MEASUREMENT
has-value: Mode Circularity

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 105.0 ± 6.042
has-unit: %

HYDRODYNAMIC_DIAMETER
type: BAO_0000179
STATO_0000035: 288.1 ± 3.74
has-unit: nm

T.INSTRUMENT_MODEL
has-value: TEM

DOSE
has-unit: mg/kg
has-value: 0.017

material
has-value: In Vitro stimulation

DLS
type: OBI_0000272

SIZE_MEASUREMENT
has-value: Median Feret Minimal Diameter

SIZE_MEASUREMENT
has-value: Mean ECD

GLOBAL_MEAN_SIZE
type: BAO_0000179
STATO_0000035: 295.0 ± 9.09
has-unit: nm

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 4.24

UNITO_LDH_NM100_RAW_24H
publisher: CNR

FERET_MINIMAL_DIAMETER
type: BAO_0000179
STATO_0000035: 102.0 ± 3.0
has-unit: nm

SIZE_MEASUREMENT
has-value: Mean Roundness

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 10.0

SIZE_MEASUREMENT
has-value: Batch dispersion size distribution

material
has-value: none

BATCH_DISPERSION_SIZE_DISTRIBUTION
type: BAO_0000179
STATO_0000035: 240.4 ± 2.9
has-unit: nm

material
has-value: In Vitro stimulation

SIZE_MEASUREMENT
has-value: Median Feret Minimal Diameter

SIZE_MEASUREMENT
has-value: Mode Feret Minimal Diameter

BATCH_DISPERSION_SIZE_DISTRIBUTION
type: BAO_0000179
STATO_0000035: 244.9 ± 2.3
has-unit: nm

Benchmarking_JRCNM01000a_TEK_1
publisher: TEKNIKER

LDH
type: OBI_0000272

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 7.758

FERET_MINIMAL_DIAMETER
type: BAO_0000179
STATO_0000035: 115.9 ± 8.2
has-unit: nm

SIZE_MEASUREMENT_TYPE
has-value: size distribution

SIZE_MEASUREMENT_TYPE
has-value: shape

E.ANIMAL_MODEL
has-value: rat

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 0.42

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 50.0

VIABILITY
type: ENM_0000068
type: BAO_0000015
source: UNITO_LDH_NM100_RAW_24H
BAO_0002846: LDH

Provided
publisher: Fraunhofer
publisher: JRC - IHCP

SIZE
type: CHMO_0002119
type: BAO_0000015
source: NM100_CA_TK6_11
BAO_0002846: DLS

SIZE
type: CHMO_0002119
type: BAO_0000015
source: ILC_Phase3_CODA_Agg
BAO_0002846: TEM

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 100.0 ± 0.0
has-unit: %

SIZE_MEASUREMENT
has-value: Z-ave hydrodynamic diameter

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

PERCENTAGE_VIABILITY_COMPARED_TO_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-unit: %
has-value: 53.987

material
has-value: In Vitro stimulation

SIZE_MEASUREMENT_TYPE
has-value: shape

NM100_CA_TK6_24hr_11
publisher: CBT

material
has-value: In Vitro stimulation

SIZE_MEASUREMENT
has-value: Median ECD

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 16.243 ± 0.749
has-unit: %

SIZE_MEASUREMENT_TYPE
has-value: size distribution

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 1.41

PERCENTAGE_VIABILITY_COMPARED_TO_CONTROL
type: BAO_0000179
has-unit: % DNA in Tail
has-value: 7.05632460494903

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 2.99

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 1.0

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 5.849 ± 0.479
has-unit: %

SIZE_MEASUREMENT
has-value: Median Aspect Ratio

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

POLYMORPHISM
type: BAO_0000179
has-value: anatase

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 83.72 ± 0.395
has-unit: %

SIZE
type: CHMO_0002119
type: BAO_0000015
source: NM100_CA_TK6_8
BAO_0002846: DLS

SIZE_MEASUREMENT
has-value: Median ECD

SIZE
type: CHMO_0002119
type: BAO_0000015
source: JRCNM01000a_Agglomerates
BAO_0002846: TEM

SIZE_MEASUREMENT
has-value: global mean size

BATCH_DISPERSION_SIZE_DISTRIBUTION
type: BAO_0000179
STATO_0000035: 297.3 ± 9.887
has-unit: nm

concentration
has-value: 0 ug/ml

FERET_MINIMAL_DIAMETER
type: BAO_0000179
STATO_0000035: 186.3 ± 67.2
has-unit: nm

FERET_MINIMAL_DIAMETER
type: BAO_0000179
STATO_0000035: 96.0 ± 4.0
has-unit: nm

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 1.41

T.INSTRUMENT_MODEL
has-value: Batch Dispersion Quality

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 1.0

NO_CONCENTRATION
type: BAO_0000179
has-condition: CONCENTRATION
STATO_0000035: 2.35 ± 0.392
has-unit: uM(10^-6 mol)/L

material
has-value: none

GENDER
has-value: Male

material
has-value: In Vitro stimulation

ANALYSIS_ALGORITHM

material
has-value: In Vitro stimulation

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 4.24

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 14.14

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 10.0

T.INSTRUMENT_MODEL
has-value: TEM

T.INSTRUMENT_MODEL
has-value: Batch Dispersion Quality

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

VIABILITY
type: ENM_0000068
type: BAO_0000015
source: NM100_AB_A549_3h_7
BAO_0002846: Alamar Blue

T.INSTRUMENT_MODEL
has-value: Batch Dispersion Quality

material
has-value: In Vitro stimulation

SIZE_MEASUREMENT
has-value: Mean Feret Minimal Diameter

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 7.203

material
has-value: In Vitro stimulation

material
has-value: none

HYDRODYNAMIC_DIAMETER
type: BAO_0000179
STATO_0000035: 239.8 ± 2.4
has-unit: nm

SIZE_MEASUREMENT_TYPE
has-value: shape

T.INSTRUMENT_MODEL
has-value: TEM

T.INSTRUMENT_MODEL
has-value: TEM

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

CONCENTRATION
has-unit: ug/cm2
has-value: 0.3

NO_CONCENTRATION
type: BAO_0000179
has-condition: CONCENTRATION
STATO_0000035: 2.035 ± 0.583
has-unit: uM(10^-6 mol)/L

concentration
has-value: 0 ug/ml

material
has-value: Positive control

material
has-value: In Vitro stimulation

CONCENTRATION
has-unit: ug/cm2
has-value: 0.1

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 4.603

SIZE_MEASUREMENT
has-value: Z-ave hydrodynamic diameter

TOTAL_NUMBER_OF_CELLS_IN_BAL
type: BAO_0000179
has-condition: DOSE
STATO_0000035: 8360000.0 ± 1310000.0

material
has-value: In Vitro stimulation

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 1.0

DIAMETER
type: BAO_0000179
STATO_0000035: 50.0-150.0
has-unit: nm
has-value: 50-150 nm

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

CIRCULARITY
type: BAO_0000179
STATO_0000035: 0.84 ± 0.02

SIZE_MEASUREMENT
has-value: global mean size

NM100_CA-Fpg_TK6_3hr_11
publisher: CBT

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 10.129

material
has-value: In Vitro stimulation

material
has-value: In Vitro stimulation

material
has-value: none

SIZE_MEASUREMENT
has-value: Median ECD

material
has-value: In Vitro stimulation

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 4.24

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 25.0

VIABILITY
type: ENM_0000068
type: BAO_0000015
source: NM100_AB_A549_3h_6
BAO_0002846: Alamar Blue

ROUNDNESS
type: BAO_0000179
STATO_0000035: 0.71 ± 0.04

T.INSTRUMENT_MODEL
has-value: TEM

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 4.24

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

SIZE_MEASUREMENT
has-value: Mean Roundness

material
has-value: none

material
has-value: In Vitro stimulation

T.INSTRUMENT_MODEL
has-value: TEM

T.INSTRUMENT_MODEL
has-value: TEM

TEM
type: OBI_0000272

SPECIFIC_SURFACE_AREA
type: NPO 1235
type: BAO_0000015
source: Provided
BAO_0002846: NANoREG supplier

SIZE_MEASUREMENT
has-value: Mode ECD

material
has-value: none

Batch Dispersion Quality
type: OBI_0000272

T.INSTRUMENT_MODEL
has-value: DLS

material
has-value: Negative control

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 68.0 ± 4.58
has-unit: %

PERCENTAGE_VIABILITY_COMPARED_TO_CONTROL
type: BAO_0000179
has-unit: % DNA in Tail
has-value: 14.25

SIZE_MEASUREMENT
has-value: Median Feret Minimal Diameter

material
has-value: In Vitro stimulation

FERET_MINIMAL_DIAMETER
type: BAO_0000179
STATO_0000035: 88.9 ± 2.6
has-unit: nm

PERCENTAGE_VIABILITY_COMPARED_TO_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-unit: %
has-value: 10.54

T.INSTRUMENT_MODEL
has-value: TEM

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 14.14

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 3.712

JRCNM01000a_Agglomerates
publisher: INL

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 100.0 ± 0.0
has-unit: %

SIZE_MEASUREMENT_TYPE
has-value: shape

FERET_MINIMAL_DIAMETER
type: BAO_0000179
STATO_0000035: 165.1 ± 26.7
has-unit: nm

material
has-value: In Vitro stimulation

material
has-value: In Vitro stimulation

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 102.0 ± 2.56
has-unit: %

material
has-value: none

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 42.41

GENOTOXICITY
type: BAO_0002167
type: BAO_0000015
source: NM100_CA-Fpg_TK6_24hr_11
BAO_0002846: DNA Strand breaks

SIZE_MEASUREMENT_TYPE
has-value: shape

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 70.69

INERIS-IT-NM101
publisher: INERIS

nominal diameter & length
type: CHMO_0002119
type: BAO_0000015
source: Provided
BAO_0002846: NANoREG supplier

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

ROUNDNESS
type: BAO_0000179
STATO_0000035: 0.72 ± 0.06

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 27.666

CONCENTRATION
has-unit: ug/cm2
has-value: 1.0

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 20.825

NM100_CA_TK6_24hr_8
publisher: CBT

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 13.227 ± 3.434
has-unit: %

material
has-value: none

SIZE_MEASUREMENT
has-value: Median Circularity

NM100RPMI100/24
publisher: CNR

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 18.696 ± 5.082
has-unit: %

ASPECT_RATIO_D1_D3
type: BAO_0000179
STATO_0000035: 0.8 ± 0.02

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 3.223

T.INSTRUMENT_MODEL
has-value: TEM

JRCNM01000a
publisher: INMETRO
publisher: NRCWE

SIZE_MEASUREMENT
has-value: Batch dispersion size distribution

material
has-value: In Vitro stimulation

SIZE_MEASUREMENT
has-value: Mean ECD

concentration
has-value: 0 ug/ml

BATCH_DISPERSION_SIZE_DISTRIBUTION
type: BAO_0000179
STATO_0000035: 497.5 ± 1573.0
has-unit: nm

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 0.0

T.INSTRUMENT_MODEL
has-value: TEM

SIZE_MEASUREMENT
has-value: Batch dispersion size distribution

ANALYSIS_ALGORITHM

material
has-value: none

ECD
type: BAO_0000179
STATO_0000035: 139.0 ± 2.0
has-unit: nm

T.INSTRUMENT_MODEL
has-value: TEM

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 0.0

SIZE_MEASUREMENT_TYPE
has-value: shape

Alamar Blue
type: OBI_0000272

SIZE_MEASUREMENT_TYPE
has-value: size distribution

E.ANIMAL_MODEL
has-value: rat

IMMUNOTOXICITY
type: NPO 1339
type: BAO_0000015
source: UNITO_NO_NM100_RAW_48H
BAO_0002846: NO production

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 141.37

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 21.194

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 10.0

concentration
has-value: 0 ug/ml

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

material
has-value: Negative control

ANALYSIS_ALGORITHM

material
has-value: In Vitro stimulation

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 73.09 ± 4.062
has-unit: %

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 0.14

ASPECT_RATIO_D1_D3
type: BAO_0000179
STATO_0000035: 0.66 ± 0.05

SIZE_MEASUREMENT
has-value: Z-ave hydrodynamic diameter

material
has-value: In Vitro stimulation

GENOTOXICITY
type: BAO_0002167
type: BAO_0000015
source: NM100_CA-Fpg_TK6_24hr_8
BAO_0000209: NRTR-00000000-0000-0000-0000-000000001165
BAO_0002846: DNA Strand breaks

concentration
has-value: 0 ug/ml

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 0.14

T.INSTRUMENT_MODEL
has-value: Batch Dispersion Quality

T.INSTRUMENT_MODEL
has-value: TEM

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 96.0 ± 2.592
has-unit: %

GENDER
has-value: Male

material
has-value: In Vitro stimulation

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 0.42

material
has-value: In Vitro stimulation

material
has-value: Negative control

T.INSTRUMENT_MODEL
has-value: TEM

T.INSTRUMENT_MODEL
has-value: TEM

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 0.0

T.INSTRUMENT_MODEL
has-value: TEM

SIZE_MEASUREMENT
has-value: Batch dispersion size distribution

T.INSTRUMENT_MODEL
has-value: Batch Dispersion Quality

material
has-value: In Vitro stimulation

SIZE_MEASUREMENT
has-value: Mode ECD

SIZE_MEASUREMENT
has-value: Mean Feret Minimal Diameter

material
has-value: none

T.INSTRUMENT_MODEL
has-value: TEM

T.INSTRUMENT_MODEL
has-value: TEM

Polymorphism
type: NPO 1512
type: BAO_0000015
source: Provided
BAO_0002846: NANoREG supplier

GENOTOXICITY
type: BAO_0002167
type: BAO_0000015
source: NM100_CA_A549_24h_7
BAO_0002846: DNA Strand breaks

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 11.598

SIZE_MEASUREMENT_TYPE
has-value: size distribution

concentration
has-value: 0 ug/ml

FERET_MINIMAL_DIAMETER
type: BAO_0000179
STATO_0000035: 124.6 ± 7.8
has-unit: nm

DNA Strand breaks
type: OBI_0000272

material
has-value: Positive control

material
has-value: none

CONCENTRATION
has-unit: ug/cm2
has-value: 10.0

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 141.37

TEST_TYPE
has-value: automatic count

material
has-value: In Vitro stimulation

SHAPE
type: NPO 274
type: BAO_0000015
source: ILC_Phase3_CODA_Agg
BAO_0002846: TEM

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 102.0 ± 4.487
has-unit: %

T.INSTRUMENT_MODEL
has-value: DLS

PERCENTAGE_VIABILITY_COMPARED_TO_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-unit: %
has-value: 77.98364

material
has-value: none

SIZE_MEASUREMENT
has-value: Mode Feret Minimal Diameter

material
has-value: In Vitro stimulation

UNITO_LDH_NM100_THP_48H
publisher: CNR

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 0.42

GLOBAL_MEAN_SIZE
type: BAO_0000179
STATO_0000035: 5210.0 ± 468.1
has-unit: nm

T.INSTRUMENT_MODEL
has-value: TEM

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 0.42

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 18.398 ± 1.35
has-unit: %

PERCENTAGE_VIABILITY_COMPARED_TO_CONTROL
type: BAO_0000179
has-unit: % DNA in Tail
has-value: 6.24

SIZE_MEASUREMENT
has-value: Mode Circularity

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 9.603

SIZE_MEASUREMENT_TYPE
has-value: size distribution

T.INSTRUMENT_MODEL
has-value: TEM

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 104.03 ± 2.637
has-unit: %

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 74.63 ± 0.027
has-unit: %

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 6.548 ± 0.84
has-unit: %

T.INSTRUMENT_MODEL
has-value: TEM

T.INSTRUMENT_MODEL
has-value: DLS

SIZE
type: CHMO_0002119
type: BAO_0000015
source: ILC phase 3 - Inmetro_Agg
BAO_0000209: NRDM-00000000-0000-0000-0000-000000001765
BAO_0002846: TEM

material
has-value: Negative control

ANALYSIS_ALGORITHM
has-value: General purpose mode

NM100_CA-Fpg_TK6_3hr_8
publisher: CBT

ECD
type: BAO_0000179
STATO_0000035: 127.0 ± 4.0
has-unit: nm

material
has-value: none

NO_CONCENTRATION
type: BAO_0000179
has-condition: CONCENTRATION
STATO_0000035: 2.495 ± 0.397
has-unit: uM(10^-6 mol)/L

TEM
type: OBI_0000272

SIZE_MEASUREMENT
has-value: Mean ECD

Alamar Blue
type: OBI_0000272

material
has-value: none

SIZE_MEASUREMENT_TYPE
has-value: intensity-weighted size distribution

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 100.0 ± 0.0
has-unit: %

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 1.41

SIZE_MEASUREMENT_TYPE
has-value: size distribution

material
has-value: In Vitro stimulation

CONCENTRATION
has-unit: ug/cm2
has-value: 10.0

material
has-value: none

DLS
type: OBI_0000272

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 4.24

ECD
type: BAO_0000179
STATO_0000035: 106.0 ± 3.0
has-unit: nm

T.INSTRUMENT_MODEL
has-value: TEM

SIZE_MEASUREMENT_TYPE
has-value: shape

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 7.854

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

VIABILITY
type: ENM_0000068
type: BAO_0000015
source: UNITO_LDH_NM100_RAW_48H
BAO_0002846: LDH

CONCENTRATION
has-unit: ug/cm2
has-value: 0.1

TOTAL_NUMBER_OF_CELLS_IN_BAL
type: BAO_0000179
has-condition: DOSE
STATO_0000035: 5840000.0 ± 940000.0

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 6.653

T.INSTRUMENT_MODEL
has-value: Batch Dispersion Quality

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 106.0 ± 29.139
has-unit: %

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

ECD
type: BAO_0000179
STATO_0000035: 129.9 ± 6.7
has-unit: nm

GLOBAL_MEAN_SIZE
type: BAO_0000179
STATO_0000035: 288.1 ± 0.181
has-unit: nm

ROUNDNESS
type: BAO_0000179
STATO_0000035: 0.79 ± 0.02

T.INSTRUMENT_MODEL
has-value: DLS

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 20.825

material
has-value: none

DLS
type: OBI_0000272

SIZE_MEASUREMENT
has-value: Mean Aspect Ratio

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 0.42

T.INSTRUMENT_MODEL
has-value: TEM

SIZE
type: CHMO_0002119
type: BAO_0000015
source: JRCNM01000a
BAO_0000209: NRDM-00000000-0000-0000-0000-000000001778
BAO_0002846: DLS

SOLIDITY
type: BAO_0000179
STATO_0000035: 0.92 ± 0.04

material
has-value: In Vitro stimulation

T.INSTRUMENT_MODEL
has-value: TEM

concentration
has-value: 0 ug/ml

Alamar Blue
type: OBI_0000272

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 27.666

T.INSTRUMENT_MODEL
has-value: TEM

NANOGENOTOX_Dispersion_SINTEF_NM100
publisher: SINTEF

material
has-value: none

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 57.0 ± 3.432
has-unit: %

SHAPE
type: NPO 274
type: BAO_0000015
source: ILC_Phase3_CODA_PP
BAO_0002846: TEM

T.INSTRUMENT_MODEL
has-value: TEM

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 1.41

ECD
type: BAO_0000179
STATO_0000035: 145.4 ± 49.7
has-unit: nm

UNITO_NO_NM100_RAW_24H
publisher: CNR

ANALYSIS_ALGORITHM

PERCENTAGE_VIABILITY_COMPARED_TO_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-unit: %
has-value: 4.365

SIZE_MEASUREMENT_TYPE
has-value: shape

material
has-value: In Vitro stimulation

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 106.0 ± 6.394
has-unit: %

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 14.14

Batch Dispersion Quality
type: OBI_0000272

concentration
has-value: 0 ug/ml

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

material
has-value: Negative control

ANALYSIS_ALGORITHM

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 42.41

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 44.614

SIZE_MEASUREMENT
has-value: Batch dispersion size distribution

NO_CONCENTRATION
type: BAO_0000179
has-condition: CONCENTRATION
STATO_0000035: 2.995 ± 0.422
has-unit: uM(10^-6 mol)/L

material
has-value: In Vitro stimulation

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 27.699

ORGANIC_COAT./ASS._ORGANICS
type: BAO_0000179
has-value: no

SIZE_MEASUREMENT
has-value: Z-ave hydrodynamic diameter

SIZE_MEASUREMENT
has-value: Batch dispersion size distribution

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 23.482 ± 2.356
has-unit: %

T.INSTRUMENT_MODEL
has-value: TEM

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 28.091 ± 11.433
has-unit: %

ASPECT_RATIO_D1_D3
type: BAO_0000179
STATO_0000035: 0.86 ± 0.03

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 6.146

T.INSTRUMENT_MODEL
has-value: Batch Dispersion Quality

ECD
type: BAO_0000179
STATO_0000035: 95.0 ± 3.0
has-unit: nm

material
has-value: In Vitro stimulation

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 141.37

material
has-value: Negative control

SIZE_MEASUREMENT
has-value: Mean Solidity

T.INSTRUMENT_MODEL
has-value: TEM

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 100.0

SIZE_MEASUREMENT
has-value: Batch dispersion size distribution

material
has-value: In Vitro stimulation

T.INSTRUMENT_MODEL
has-value: Batch Dispersion Quality

SIZE_MEASUREMENT
has-value: Mode ECD

SIZE_MEASUREMENT
has-value: Median ECD

SIZE_MEASUREMENT_TYPE
has-value: size distribution

GENOTOXICITY
type: BAO_0002167
type: BAO_0000015
source: NM100_CA_A549_3h_6
BAO_0002846: DNA Strand breaks

FERET_MINIMAL_DIAMETER
type: BAO_0000179
STATO_0000035: 130.0 ± 3.0
has-unit: nm

HYDRODYNAMIC_DIAMETER
type: BAO_0000179
STATO_0000035: 241.4 ± 1.6
has-unit: nm

ILC_Phase3_CODA_PP
publisher: CODA-CERVA

CONCENTRATION
has-unit: ug/cm2
has-value: 1.0

NO_CONCENTRATION
type: BAO_0000179
has-condition: CONCENTRATION
STATO_0000035: 2.417 ± 0.729
has-unit: uM(10^-6 mol)/L

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 14.14

TEST_TYPE
has-value: automatic count

JRCNM01000a_Agg
publisher: NRCWE

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 22.663

material
has-value: In Vitro stimulation

ECD
type: BAO_0000179
STATO_0000035: 187.6 ± 28.5
has-unit: nm

SIZE_MEASUREMENT_TYPE
has-value: shape

NM100_CA_A549_3h_6
publisher: NILU

DNA Strand breaks
type: OBI_0000272

SIZE_MEASUREMENT
has-value: Median Feret Minimal Diameter

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 105.0 ± 2.355
has-unit: %

SIZE_MEASUREMENT_TYPE
has-value: size distribution

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 17.75

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 50.0

SIZE_MEASUREMENT
has-value: Median Circularity

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

PURITY_OF_PARTICLES
type: BAO_0000179
has-unit: wt%
has-value: 2.3

NM100_CA_TK6_11
publisher: CBT

CIRCULARITY
type: BAO_0000179
STATO_0000035: 0.68 ± 0.1

TEM
type: OBI_0000272

DNA Strand breaks
type: OBI_0000272

T.INSTRUMENT_MODEL
has-value: Batch Dispersion Quality

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 0.0

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 50.0

material
has-value: none

material
has-value: In Vitro stimulation

SIZE_MEASUREMENT
has-value: Mode Feret Minimal Diameter

SIZE_MEASUREMENT
has-value: Z-ave hydrodynamic diameter

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 86.46 ± 17.869
has-unit: %

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 0.14

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 100.0

ECD
type: BAO_0000179
STATO_0000035: 86.3 ± 5.1
has-unit: nm

ILC_Phase3_CODA_Agg
publisher: CODA-CERVA

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

T.INSTRUMENT_MODEL
has-value: Batch Dispersion Quality

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 0.42

material
has-value: In Vitro stimulation

CONCENTRATION
has-unit: ug/cm2
has-value: 1.0

material
has-value: none

material
has-value: In Vitro stimulation

BATCH_DISPERSION_SIZE_DISTRIBUTION
type: BAO_0000179
STATO_0000035: 496.2 ± 1532.0
has-unit: nm

T.INSTRUMENT_MODEL
has-value: TEM

SIZE_MEASUREMENT_TYPE
has-value: shape

T.INSTRUMENT_MODEL
has-value: TEM

CONCENTRATION
has-unit: ug/cm2
has-value: 10.0

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 100.0 ± 0.0
has-unit: %

NO_CONCENTRATION
type: BAO_0000179
has-condition: POSITIVE_CONTROL_CONCENTRATION
has-condition: CONCENTRATION
STATO_0000035: 228.585 ± 3.987
has-unit: uM(10^-6 mol)/L

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 15.575

material
has-value: In Vitro stimulation

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

UNITO_NO_NM100_RAW_48H
publisher: CNR

material
has-value: none

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 106.0 ± 2.335
has-unit: %

SIZE_MEASUREMENT
has-value: Mode Solidity

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 15.326

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 141.37

T.INSTRUMENT_MODEL
has-value: TEM

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 70.69

material
has-value: none

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 24.393 ± 0.625
has-unit: %

material
has-value: In Vitro stimulation

T.INSTRUMENT_MODEL
has-value: TEM

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 17.999

SIZE_MEASUREMENT
has-value: Mode Feret Minimal Diameter

material
has-value: none

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 108.62 ± 0.024
has-unit: %

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 9.376 ± 0.742
has-unit: %

SOLIDITY
type: BAO_0000179
STATO_0000035: 0.96 ± 0.0

material
has-value: none

SIZE_MEASUREMENT_TYPE
has-value: intensity-weighted size distribution

NO production
type: OBI_0000272

FERET_MINIMAL_DIAMETER
type: BAO_0000179
STATO_0000035: 122.0 ± 4.0
has-unit: nm

T.INSTRUMENT_MODEL
has-value: TEM

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 0.14

NO_CONCENTRATION
type: BAO_0000179
has-condition: CONCENTRATION
STATO_0000035: 2.013 ± 0.381
has-unit: uM(10^-6 mol)/L

GENOTOXICITY
type: BAO_0002167
type: BAO_0000015
source: NM100_CA-Fpg_TK6_3hr_8
BAO_0000209: NRTR-00000000-0000-0000-0000-000000001162
BAO_0002846: DNA Strand breaks

ANALYSIS_ALGORITHM

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 91.0 ± 5.916
has-unit: %

SIZE_MEASUREMENT_TYPE
has-value: shape

material
has-value: In Vitro stimulation

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 0.42

FERET_MINIMAL_DIAMETER
type: BAO_0000179
STATO_0000035: 102.0 ± 3.0
has-unit: nm

ANALYSIS_ALGORITHM

CONCENTRATION
has-unit: ug/cm2
has-value: 30.0

BATCH_DISPERSION_SIZE_DISTRIBUTION
type: BAO_0000179
STATO_0000035: 238.9 ± 2.6
has-unit: nm

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 4.24

BATCH_DISPERSION_SIZE_DISTRIBUTION
type: BAO_0000179
STATO_0000035: 248.2 ± 1.2
has-unit: nm

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 9.386

material
has-value: In Vitro stimulation

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 103.0 ± 1.573
has-unit: %

ECD
type: BAO_0000179
STATO_0000035: 126.4 ± 6.5
has-unit: nm

SIZE_MEASUREMENT
has-value: Batch dispersion size distribution

SIZE_MEASUREMENT
has-value: Median Roundness

T.INSTRUMENT_MODEL
has-value: TEM

DOSE
has-unit: mg/kg
has-value: 0.17

TEM
type: OBI_0000272

https://apps.ideaconsult.net/nanoreg1/interpretation/NRCR-d027f5b8-9e41-8d35-687b-b903e68c1c8d
has-value: anatase

SIZE_MEASUREMENT
has-value: Mode ECD

SIZE_MEASUREMENT
has-value: Mean Feret Minimal Diameter

SOLIDITY
type: BAO_0000179
STATO_0000035: 0.86 ± 0.2

PERCENTAGE_VIABILITY_COMPARED_TO_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-unit: %
has-value: 76.93846

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 14.14

SIZE_MEASUREMENT
has-value: Mode Roundness

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 25.0

BALL ANALYSIS
type: ENM_0000024
type: BAO_0000015
source: INERIS-IT-NM101
BAO_0002846: https://apps.ideaconsult.net/nanoreg1/protocol/F0A06CE3

SIZE_MEASUREMENT
has-value: Batch dispersion size distribution

ECOTOX_Dispersion_SINTEF_NM100
publisher: SINTEF

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 44.614

material
has-value: In Vitro stimulation

SIZE_MEASUREMENT
has-value: Mean Feret Minimal Diameter

SIZE_MEASUREMENT
has-value: Median ECD

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 32.031 ± 7.325
has-unit: %

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 81.15 ± 2.061
has-unit: %

DNA Strand breaks
type: OBI_0000272

POLYMORPHISM
type: BAO_0000179
has-value: anatase

SIZE
type: CHMO_0002119
type: BAO_0000015
source: JRCNM01000a_PP
BAO_0002846: TEM

ANALYSIS_ALGORITHM

NM100_CA-Fpg_TK6_24hr_8
publisher: CBT

FERET_MINIMAL_DIAMETER
type: BAO_0000179
STATO_0000035: 94.0 ± 4.0
has-unit: nm

Chemical composition of particles
type: ENM_0000090
type: BAO_0000015
source: Provided
BAO_0002846: NANoREG supplier

FERET_MINIMAL_DIAMETER
type: BAO_0000179
STATO_0000035: 157.3 ± 51.9
has-unit: nm

SIZE_MEASUREMENT_TYPE
has-value: size distribution

NO_CONCENTRATION
type: BAO_0000179
has-condition: CONCENTRATION
STATO_0000035: 2.065 ± 0.548
has-unit: uM(10^-6 mol)/L

CONCENTRATION
has-unit: ug/cm2
has-value: 0.1

TEM
type: OBI_0000272

E.ANIMAL_MODEL
has-value: rat

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 1.41

TEM
type: OBI_0000272

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 100.0

material
has-value: In Vitro stimulation

NM100_CA_A549_24h_6
publisher: NILU

SIZE_MEASUREMENT_TYPE
has-value: shape

SIZE_MEASUREMENT_TYPE
has-value: size distribution

material
has-value: In Vitro stimulation

SIZE_MEASUREMENT
has-value: Mean ECD

DNA Strand breaks
type: OBI_0000272

SIZE_MEASUREMENT_TYPE
has-value: size distribution

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 4.24

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 5.88

Benchmarking_JRCNM01000a_TEK_3
publisher: TEKNIKER

DISPERSION QUALITY
type: CHMO_0002119
type: BAO_0000015
source: Benchmarking_JRCNM01000a_TEK_1
BAO_0002846: Batch Dispersion Quality

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 10.0

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 0.0

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

SIZE_MEASUREMENT
has-value: Mean Aspect Ratio

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

T.INSTRUMENT_MODEL
has-value: Batch Dispersion Quality

SIZE_MEASUREMENT
has-value: Mean ECD

NO_CONCENTRATION
type: BAO_0000179
has-condition: CONCENTRATION
STATO_0000035: 2.952 ± 0.914
has-unit: uM(10^-6 mol)/L

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 42.41

concentration
has-value: 0 ug/ml

T.INSTRUMENT_MODEL
has-value: Batch Dispersion Quality

TOTAL_NUMBER_OF_CELLS_IN_BAL
type: BAO_0000179
has-condition: DOSE
STATO_0000035: 8480000.0 ± 1250000.0

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 10.0

material
has-value: none

T.INSTRUMENT_MODEL
has-value: Batch Dispersion Quality

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 27.797 ± 2.011
has-unit: %

material
has-value: In Vitro stimulation

SIZE_MEASUREMENT
has-value: Median Feret Minimal Diameter

CIRCULARITY
type: BAO_0000179
STATO_0000035: 0.8 ± 0.02

ANALYSIS_ALGORITHM

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 8.778

POSITIVE_CONTROL_CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 1.0

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 14.14

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 42.41

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 25.0

T.INSTRUMENT_MODEL
has-value: TEM

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

T.INSTRUMENT_MODEL
has-value: Batch Dispersion Quality

material
has-value: In Vitro stimulation

SIZE_MEASUREMENT
has-value: Mode Feret Minimal Diameter

CONCENTRATION
has-unit: ug/cm2
has-value: 0.1

material
has-value: In Vitro stimulation

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 141.37

T.INSTRUMENT_MODEL
has-value: TEM

SIZE_MEASUREMENT_TYPE
has-value: shape

T.INSTRUMENT_MODEL
has-value: TEM

NM100_AB_A549_24h_7
publisher: NILU

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

CONCENTRATION
has-unit: ug/cm2
has-value: 1.0

SIZE_MEASUREMENT_TYPE
has-value: size distribution

concentration
has-value: 0 ug/ml

FERET_MINIMAL_DIAMETER
type: BAO_0000179
STATO_0000035: 131.0 ± 2.0
has-unit: nm

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 88.0 ± 6.19
has-unit: %

material
has-value: In Vitro stimulation

PERCENTAGE_VIABILITY_COMPARED_TO_CONTROL
type: BAO_0000179
has-unit: % DNA in Tail
has-value: 16.2

material
has-value: In Vitro stimulation

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 10.0

FERET_MINIMAL_DIAMETER
type: BAO_0000179
STATO_0000035: 110.0 ± 5.9
has-unit: nm

PERCENTAGE_VIABILITY_COMPARED_TO_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-unit: %
has-value: 8.09367539505097

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

material
has-value: In Vitro stimulation

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 3.12

material
has-value: In Vitro stimulation

material
has-value: none

INORGANIC_COAT./ASS._ELEMENTS
type: BAO_0000179
has-value: Fe,Si,Al

SIZE_MEASUREMENT
has-value: Median Solidity

ECD
type: BAO_0000179
STATO_0000035: 186.6 ± 32.0
has-unit: nm

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 14.14

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 103.0 ± 1.52
has-unit: %

NANoREG supplier
type: OBI_0000272

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 50.0

T.INSTRUMENT_MODEL
has-value: TEM

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 14.14

SIZE_MEASUREMENT
has-value: Mode Roundness

material
has-value: none

material
has-value: In Vitro stimulation

T.INSTRUMENT_MODEL
has-value: TEM

NM100_CA_A549_3h_7
publisher: NILU

SIZE_MEASUREMENT
has-value: Median Feret Minimal Diameter

material
has-value: none

CIRCULARITY
type: BAO_0000179
STATO_0000035: 0.86 ± 0.13

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 27.699

NM100_CA_TK6_5
publisher: CBT

material
has-value: Positive control

SIZE_MEASUREMENT
has-value: Mean Feret Minimal Diameter

DNA Strand breaks
type: OBI_0000272

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 12.366

GENOTOXICITY
type: BAO_0002167
type: BAO_0000015
source: NM100_CA_TK6_24hr_11
BAO_0000209: NRTR-00000000-0000-0000-0000-000000001169
BAO_0002846: DNA Strand breaks

T.INSTRUMENT_MODEL
has-value: TEM

T.INSTRUMENT_MODEL
has-value: DLS

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 89.0 ± 0.327
has-unit: %

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 42.41

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 22.338 ± 10.069
has-unit: %

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 3.59

SIZE_MEASUREMENT_TYPE
has-value: shape

ANALYSIS_ALGORITHM

material
has-value: In Vitro stimulation

material
has-value: In Vitro stimulation

material
has-value: none

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 141.37

BATCH_DISPERSION_SIZE_DISTRIBUTION
type: BAO_0000179
STATO_0000035: 287.7 ± 9.649
has-unit: nm

NM100_CA_A549_24h_7
publisher: NILU

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

ANALYSIS_ALGORITHM

CONCENTRATION
has-unit: ug/cm2
has-value: 3.0

ECD
type: BAO_0000179
STATO_0000035: 139.0 ± 2.0
has-unit: nm

SIZE_MEASUREMENT_TYPE
has-value: Monomodal

SIZE_MEASUREMENT
has-value: Mean Circularity

T.INSTRUMENT_MODEL
has-value: TEM

SIZE_MEASUREMENT
has-value: Batch dispersion size distribution

DOSE
has-unit: mg/kg
has-value: 0.0

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 19.878

material
has-value: In Vitro stimulation

HYDRODYNAMIC_DIAMETER
type: BAO_0000179
STATO_0000035: 238.8 ± 1.62
has-unit: nm

SIZE_MEASUREMENT
has-value: Median ECD

SIZE_MEASUREMENT
has-value: Mode ECD

concentration
has-value: 0 ug/ml

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 13.465 ± 1.922
has-unit: %

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 1.0

DNA_STRAND_BREAKS
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
has-unit: %
has-value: 24.681

T.INSTRUMENT_MODEL
has-value: TEM

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 78.87 ± 1.332
has-unit: %

material
has-value: none

material
has-value: In Vitro stimulation

ASPECT_RATIO_D1_D3
type: BAO_0000179
STATO_0000035: 0.71 ± 0.06

FERET_MINIMAL_DIAMETER
type: BAO_0000179
STATO_0000035: 126.0 ± 4.0
has-unit: nm

CONCENTRATION
standardised unit: MicrogramPerMilliliter
has-unit: ug/ml
has-value: 1.0

SPECIFIC_SURFACE_AREA
type: NPO 1235
type: BAO_0000015
source: Provided
BAO_0002846: NANoREG supplier

GENOTOXICITY
type: BAO_0002167
type: BAO_0000015
source: NM100_CA_TK6_24hr_8
BAO_0000209: NRTR-00000000-0000-0000-0000-000000001164
BAO_0002846: DNA Strand breaks

SIZE_MEASUREMENT_TYPE
has-value: size distribution

SIZE_MEASUREMENT_TYPE
has-value: shape

PERCENTAGE_OF_CONTROL
type: BAO_0000179
standardised unit: floatPercentage
has-condition: CONCENTRATION
STATO_0000035: 103.0 ± 9.191
has-unit: %