{"facet": [
	{
	"value":"6.1.1. Short-term toxicity to fish",	"endpoint":"EC_FISHTOX_SECTION",
	"count":5,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=EC_FISHTOX_SECTION",
	"subcategory":"ECOTOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-b51c669c-4873-3125-84cc-6f01c243aa9d/study?top=ECOTOX",	"substance":"control",	"reference":"Eawag-fish-OECD; Fish Embryo Acute Toxicity (FET) Test,Eawag-fish-zFET",	"provider":"EAWAG",	"protocol":"!!! SOP MISSING !!!,OECD 236: Fish Embryo Acute Toxicity (FET) Test",	"publicname":"CONTROL",	"substancetype":"CHEBI_59999",	"substance_uuid":"CLBR-b51c669c-4873-3125-84cc-6f01c243aa9d",	"substance_owner":"caLIBRAte"	},
	{
	"value":"4.5. Particle size distribution (Granulometry)",	"endpoint":"PC_GRANULOMETRY_SECTION",
	"count":3,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=PC_GRANULOMETRY_SECTION",
	"subcategory":"P-CHEM",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-b51c669c-4873-3125-84cc-6f01c243aa9d/study?top=P-CHEM",	"substance":"control",	"reference":"EAWAG_Nanoreg _template_Environmental_Toxicity_EAWAG_BATCH1 Sheet: water-fish-DRerio",	"provider":"EAWAG",	"protocol":"n.a.",	"publicname":"CONTROL",	"substancetype":"CHEBI_59999",	"substance_uuid":"CLBR-b51c669c-4873-3125-84cc-6f01c243aa9d",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.2.2. Acute toxicity - inhalation",	"endpoint":"TO_ACUTE_INHAL_SECTION",
	"count":7,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_ACUTE_INHAL_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-b51c669c-4873-3125-84cc-6f01c243aa9d/study?top=TOX",	"substance":"control",	"reference":"NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#Histopathology,NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#mRNA expression in vivo",	"provider":"FIOH",	"protocol":"pulmonary toxicity-Histopathology,pulmonary toxicity-Quantitative PCR",	"publicname":"CONTROL",	"substancetype":"CHEBI_59999",	"substance_uuid":"CLBR-b51c669c-4873-3125-84cc-6f01c243aa9d",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.6.2. Genetic toxicity in vivo",	"endpoint":"TO_GENETIC_IN_VIVO_SECTION",
	"count":8,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_GENETIC_IN_VIVO_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-b51c669c-4873-3125-84cc-6f01c243aa9d/study?top=TOX",	"substance":"control",	"reference":"FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1,FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1 Sheet: Micronuclei,NRCWE_in_vivo_genotoxic_FINAL.xlsx#COMET",	"provider":"FIOH,NRCWE",	"protocol":"COMET,Gamma-H2AX,OECD TG 474",	"publicname":"CONTROL",	"substancetype":"CHEBI_59999",	"substance_uuid":"CLBR-b51c669c-4873-3125-84cc-6f01c243aa9d",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.5.2. Repeated dose toxicity - inhalation",	"endpoint":"TO_REPEATED_INHAL_SECTION",
	"count":11,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_REPEATED_INHAL_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-b51c669c-4873-3125-84cc-6f01c243aa9d/study?top=TOX",	"substance":"control",	"reference":",NRCWE-Cellularity-BAL cell celularity,NRCWEcell counts-BAL cell celularity,UH-Cellularity-BAL cell celularity,UHcell counts-BAL cell celularity",	"provider":"FIOH,NRCWE,UH",	"protocol":"BAL cell celularity,Histopathology",	"publicname":"CONTROL",	"substancetype":"CHEBI_59999",	"substance_uuid":"CLBR-b51c669c-4873-3125-84cc-6f01c243aa9d",	"substance_owner":"caLIBRAte"	},
	{
	"value":"6.3.4. Toxicity to soil microorganisms",	"endpoint":"EC_SOIL_MICRO_TOX_SECTION",
	"count":1,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=EC_SOIL_MICRO_TOX_SECTION",
	"subcategory":"ECOTOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-d846df6d-19bf-30ba-b8c1-e133e2f39f60/study?top=ECOTOX",	"substance":"Porous Silica 300nm-Me",	"reference":"NERC environmental toxicity template for FINAL.xlsx",	"provider":"NERC",	"protocol":"OECD 222",	"publicname":"NRCWE#065",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-d846df6d-19bf-30ba-b8c1-e133e2f39f60",	"substance_owner":"caLIBRAte"	},
	{
	"value":"4.1. Appearance",	"endpoint":"GI_GENERAL_INFORM_SECTION",
	"count":1,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=GI_GENERAL_INFORM_SECTION",
	"subcategory":"P-CHEM",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-d846df6d-19bf-30ba-b8c1-e133e2f39f60/study?top=P-CHEM",	"substance":"Porous Silica 300nm-Me",	"reference":"caLIBRAte",	"provider":"H2020 Calibrate",	"protocol":"",	"publicname":"NRCWE#065",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-d846df6d-19bf-30ba-b8c1-e133e2f39f60",	"substance_owner":"caLIBRAte"	},
	{
	"value":"4.5. Particle size distribution (Granulometry)",	"endpoint":"PC_GRANULOMETRY_SECTION",
	"count":63,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=PC_GRANULOMETRY_SECTION",
	"subcategory":"P-CHEM",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-d846df6d-19bf-30ba-b8c1-e133e2f39f60/study?top=P-CHEM",	"substance":"Porous Silica 300nm-Me",	"reference":",FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1,FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1 Sheet: Micronuclei,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Blood biochemistry,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Body&organ weight,LEITAT_FIOH_oral toxicity_FINAL.xlsx#COMET-Local genotoxicity,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Hematological parameters,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Histopathology,NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#Histopathology,NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#mRNA expression in vivo,NRCWE_in_vivo_genotoxic_FINAL.xlsx#COMET,OECD 222",	"provider":"FIOH,NERC,NRCWE",	"protocol":"DLS,TEM",	"publicname":"NRCWE#065",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-d846df6d-19bf-30ba-b8c1-e133e2f39f60",	"substance_owner":"caLIBRAte"	},
	{
	"value":"ENM_0000068. Cell Viability",	"endpoint":"ENM_0000068_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=ENM_0000068_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-d846df6d-19bf-30ba-b8c1-e133e2f39f60/study?top=TOX",	"substance":"Porous Silica 300nm-Me",	"reference":"Calibrate D5.6",	"provider":"MISVIK",	"protocol":"CellTiter-Glo (CTG)",	"publicname":"NRCWE#065",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-d846df6d-19bf-30ba-b8c1-e133e2f39f60",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.2.2. Acute toxicity - inhalation",	"endpoint":"TO_ACUTE_INHAL_SECTION",
	"count":7,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_ACUTE_INHAL_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-d846df6d-19bf-30ba-b8c1-e133e2f39f60/study?top=TOX",	"substance":"Porous Silica 300nm-Me",	"reference":"NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#Histopathology,NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#mRNA expression in vivo",	"provider":"FIOH",	"protocol":"pulmonary toxicity-Histopathology,pulmonary toxicity-Quantitative PCR",	"publicname":"NRCWE#065",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-d846df6d-19bf-30ba-b8c1-e133e2f39f60",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.2.1. Acute toxicity - oral",	"endpoint":"TO_ACUTE_ORAL_SECTION",
	"count":41,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_ACUTE_ORAL_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-d846df6d-19bf-30ba-b8c1-e133e2f39f60/study?top=TOX",	"substance":"Porous Silica 300nm-Me",	"reference":"LEITAT_FIOH_oral toxicity_FINAL.xlsx#Blood biochemistry,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Body&organ weight,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Hematological parameters,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Histopathology",	"provider":"LEITAT",	"protocol":"Short term oral toxicity",	"publicname":"NRCWE#065",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-d846df6d-19bf-30ba-b8c1-e133e2f39f60",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.6.2. Genetic toxicity in vivo",	"endpoint":"TO_GENETIC_IN_VIVO_SECTION",
	"count":13,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_GENETIC_IN_VIVO_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-d846df6d-19bf-30ba-b8c1-e133e2f39f60/study?top=TOX",	"substance":"Porous Silica 300nm-Me",	"reference":"FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1,FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1 Sheet: Micronuclei,LEITAT_FIOH_oral toxicity_FINAL.xlsx#COMET-Local genotoxicity,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Hyperspectral analysis,NRCWE_in_vivo_genotoxic_FINAL.xlsx#COMET",	"provider":"FIOH,LEITAT,NRCWE",	"protocol":"COMET,Gamma-H2AX,NM detection in intestinal tissue-Hyperspectral image analysis,OECD TG 474,in vivo Comet assay",	"publicname":"NRCWE#065",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-d846df6d-19bf-30ba-b8c1-e133e2f39f60",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.5.2. Repeated dose toxicity - inhalation",	"endpoint":"TO_REPEATED_INHAL_SECTION",
	"count":15,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_REPEATED_INHAL_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-d846df6d-19bf-30ba-b8c1-e133e2f39f60/study?top=TOX",	"substance":"Porous Silica 300nm-Me",	"reference":",NRCWE-Cellularity-BAL cell celularity,NRCWEcell counts-BAL cell celularity,UH-Cellularity-BAL cell celularity,UHcell counts-BAL cell celularity",	"provider":"FIOH,NRCWE,UH",	"protocol":"BAL cell celularity,Histopathology",	"publicname":"NRCWE#065",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-d846df6d-19bf-30ba-b8c1-e133e2f39f60",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.3.1. Skin irritation / Corrosion",	"endpoint":"TO_SKIN_IRRITATION_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_SKIN_IRRITATION_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-d846df6d-19bf-30ba-b8c1-e133e2f39f60/study?top=TOX",	"substance":"Porous Silica 300nm-Me",	"reference":"GAIKER_Nanoreg2_Calibrate_template irritation assays_BATCH1",	"provider":"GAIKER",	"protocol":"OECD 439,OECD 492",	"publicname":"NRCWE#065",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-d846df6d-19bf-30ba-b8c1-e133e2f39f60",	"substance_owner":"caLIBRAte"	},
	{
	"value":"4.1. Appearance",	"endpoint":"GI_GENERAL_INFORM_SECTION",
	"count":1,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=GI_GENERAL_INFORM_SECTION",
	"subcategory":"P-CHEM",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-e06ef33b-ed7b-3427-aa26-28964fd8dbf6/study?top=P-CHEM",	"substance":"Non-porous Silica 300nm-Me",	"reference":"caLIBRAte",	"provider":"H2020 Calibrate",	"protocol":"",	"publicname":"NRCWE#066",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-e06ef33b-ed7b-3427-aa26-28964fd8dbf6",	"substance_owner":"caLIBRAte"	},
	{
	"value":"4.5. Particle size distribution (Granulometry)",	"endpoint":"PC_GRANULOMETRY_SECTION",
	"count":62,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=PC_GRANULOMETRY_SECTION",
	"subcategory":"P-CHEM",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-e06ef33b-ed7b-3427-aa26-28964fd8dbf6/study?top=P-CHEM",	"substance":"Non-porous Silica 300nm-Me",	"reference":",FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1,FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1 Sheet: Micronuclei,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Blood biochemistry,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Body&organ weight,LEITAT_FIOH_oral toxicity_FINAL.xlsx#COMET-Local genotoxicity,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Hematological parameters,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Histopathology,NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#Histopathology,NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#mRNA expression in vivo,NRCWE_in_vivo_genotoxic_FINAL.xlsx#COMET",	"provider":"FIOH,NRCWE",	"protocol":"DLS,TEM",	"publicname":"NRCWE#066",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-e06ef33b-ed7b-3427-aa26-28964fd8dbf6",	"substance_owner":"caLIBRAte"	},
	{
	"value":"ENM_0000068. Cell Viability",	"endpoint":"ENM_0000068_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=ENM_0000068_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-e06ef33b-ed7b-3427-aa26-28964fd8dbf6/study?top=TOX",	"substance":"Non-porous Silica 300nm-Me",	"reference":"Calibrate D5.6",	"provider":"MISVIK",	"protocol":"CellTiter-Glo (CTG)",	"publicname":"NRCWE#066",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-e06ef33b-ed7b-3427-aa26-28964fd8dbf6",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.2.2. Acute toxicity - inhalation",	"endpoint":"TO_ACUTE_INHAL_SECTION",
	"count":7,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_ACUTE_INHAL_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-e06ef33b-ed7b-3427-aa26-28964fd8dbf6/study?top=TOX",	"substance":"Non-porous Silica 300nm-Me",	"reference":"NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#Histopathology,NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#mRNA expression in vivo",	"provider":"FIOH",	"protocol":"pulmonary toxicity-Histopathology,pulmonary toxicity-Quantitative PCR",	"publicname":"NRCWE#066",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-e06ef33b-ed7b-3427-aa26-28964fd8dbf6",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.2.1. Acute toxicity - oral",	"endpoint":"TO_ACUTE_ORAL_SECTION",
	"count":41,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_ACUTE_ORAL_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-e06ef33b-ed7b-3427-aa26-28964fd8dbf6/study?top=TOX",	"substance":"Non-porous Silica 300nm-Me",	"reference":"LEITAT_FIOH_oral toxicity_FINAL.xlsx#Blood biochemistry,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Body&organ weight,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Hematological parameters,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Histopathology",	"provider":"LEITAT",	"protocol":"Short term oral toxicity",	"publicname":"NRCWE#066",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-e06ef33b-ed7b-3427-aa26-28964fd8dbf6",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.6.2. Genetic toxicity in vivo",	"endpoint":"TO_GENETIC_IN_VIVO_SECTION",
	"count":13,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_GENETIC_IN_VIVO_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-e06ef33b-ed7b-3427-aa26-28964fd8dbf6/study?top=TOX",	"substance":"Non-porous Silica 300nm-Me",	"reference":"FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1,FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1 Sheet: Micronuclei,LEITAT_FIOH_oral toxicity_FINAL.xlsx#COMET-Local genotoxicity,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Hyperspectral analysis,NRCWE_in_vivo_genotoxic_FINAL.xlsx#COMET",	"provider":"FIOH,LEITAT,NRCWE",	"protocol":"COMET,Gamma-H2AX,NM detection in intestinal tissue-Hyperspectral image analysis,OECD TG 474,in vivo Comet assay",	"publicname":"NRCWE#066",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-e06ef33b-ed7b-3427-aa26-28964fd8dbf6",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.5.2. Repeated dose toxicity - inhalation",	"endpoint":"TO_REPEATED_INHAL_SECTION",
	"count":11,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_REPEATED_INHAL_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-e06ef33b-ed7b-3427-aa26-28964fd8dbf6/study?top=TOX",	"substance":"Non-porous Silica 300nm-Me",	"reference":",NRCWE-Cellularity-BAL cell celularity,NRCWEcell counts-BAL cell celularity,UH-Cellularity-BAL cell celularity,UHcell counts-BAL cell celularity",	"provider":"FIOH,NRCWE,UH",	"protocol":"BAL cell celularity,Histopathology",	"publicname":"NRCWE#066",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-e06ef33b-ed7b-3427-aa26-28964fd8dbf6",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.3.1. Skin irritation / Corrosion",	"endpoint":"TO_SKIN_IRRITATION_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_SKIN_IRRITATION_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-e06ef33b-ed7b-3427-aa26-28964fd8dbf6/study?top=TOX",	"substance":"Non-porous Silica 300nm-Me",	"reference":"GAIKER_Nanoreg2_Calibrate_template irritation assays_BATCH1",	"provider":"GAIKER",	"protocol":"OECD 439,OECD 492",	"publicname":"NRCWE#066",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-e06ef33b-ed7b-3427-aa26-28964fd8dbf6",	"substance_owner":"caLIBRAte"	},
	{
	"value":"4.1. Appearance",	"endpoint":"GI_GENERAL_INFORM_SECTION",
	"count":1,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=GI_GENERAL_INFORM_SECTION",
	"subcategory":"P-CHEM",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-60a46dd3-af5d-36b1-a961-aa3a38c312a8/study?top=P-CHEM",	"substance":"Porous Silica 100nm-Me",	"reference":"caLIBRAte",	"provider":"H2020 Calibrate",	"protocol":"",	"publicname":"NRCWE#067",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-60a46dd3-af5d-36b1-a961-aa3a38c312a8",	"substance_owner":"caLIBRAte"	},
	{
	"value":"4.5. Particle size distribution (Granulometry)",	"endpoint":"PC_GRANULOMETRY_SECTION",
	"count":63,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=PC_GRANULOMETRY_SECTION",
	"subcategory":"P-CHEM",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-60a46dd3-af5d-36b1-a961-aa3a38c312a8/study?top=P-CHEM",	"substance":"Porous Silica 100nm-Me",	"reference":",FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1,FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1 Sheet: Micronuclei,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Blood biochemistry,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Body&organ weight,LEITAT_FIOH_oral toxicity_FINAL.xlsx#COMET-Local genotoxicity,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Hematological parameters,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Histopathology,NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#Histopathology,NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#mRNA expression in vivo,NRCWE_in_vivo_genotoxic_FINAL.xlsx#COMET",	"provider":"FIOH,NRCWE",	"protocol":"DLS,TEM",	"publicname":"NRCWE#067",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-60a46dd3-af5d-36b1-a961-aa3a38c312a8",	"substance_owner":"caLIBRAte"	},
	{
	"value":"ENM_0000068. Cell Viability",	"endpoint":"ENM_0000068_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=ENM_0000068_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-60a46dd3-af5d-36b1-a961-aa3a38c312a8/study?top=TOX",	"substance":"Porous Silica 100nm-Me",	"reference":"Calibrate D5.6",	"provider":"MISVIK",	"protocol":"CellTiter-Glo (CTG)",	"publicname":"NRCWE#067",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-60a46dd3-af5d-36b1-a961-aa3a38c312a8",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.2.2. Acute toxicity - inhalation",	"endpoint":"TO_ACUTE_INHAL_SECTION",
	"count":7,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_ACUTE_INHAL_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-60a46dd3-af5d-36b1-a961-aa3a38c312a8/study?top=TOX",	"substance":"Porous Silica 100nm-Me",	"reference":"NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#Histopathology,NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#mRNA expression in vivo",	"provider":"FIOH",	"protocol":"pulmonary toxicity-Histopathology,pulmonary toxicity-Quantitative PCR",	"publicname":"NRCWE#067",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-60a46dd3-af5d-36b1-a961-aa3a38c312a8",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.2.1. Acute toxicity - oral",	"endpoint":"TO_ACUTE_ORAL_SECTION",
	"count":42,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_ACUTE_ORAL_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-60a46dd3-af5d-36b1-a961-aa3a38c312a8/study?top=TOX",	"substance":"Porous Silica 100nm-Me",	"reference":"LEITAT_FIOH_oral toxicity_FINAL.xlsx#Blood biochemistry,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Body&organ weight,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Hematological parameters,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Histopathology",	"provider":"LEITAT",	"protocol":"Short term oral toxicity",	"publicname":"NRCWE#067",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-60a46dd3-af5d-36b1-a961-aa3a38c312a8",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.6.2. Genetic toxicity in vivo",	"endpoint":"TO_GENETIC_IN_VIVO_SECTION",
	"count":13,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_GENETIC_IN_VIVO_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-60a46dd3-af5d-36b1-a961-aa3a38c312a8/study?top=TOX",	"substance":"Porous Silica 100nm-Me",	"reference":"FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1,FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1 Sheet: Micronuclei,LEITAT_FIOH_oral toxicity_FINAL.xlsx#COMET-Local genotoxicity,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Hyperspectral analysis,NRCWE_in_vivo_genotoxic_FINAL.xlsx#COMET",	"provider":"FIOH,LEITAT,NRCWE",	"protocol":"COMET,Gamma-H2AX,NM detection in intestinal tissue-Hyperspectral image analysis,OECD TG 474,in vivo Comet assay",	"publicname":"NRCWE#067",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-60a46dd3-af5d-36b1-a961-aa3a38c312a8",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.5.2. Repeated dose toxicity - inhalation",	"endpoint":"TO_REPEATED_INHAL_SECTION",
	"count":11,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_REPEATED_INHAL_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-60a46dd3-af5d-36b1-a961-aa3a38c312a8/study?top=TOX",	"substance":"Porous Silica 100nm-Me",	"reference":",NRCWE-Cellularity-BAL cell celularity,NRCWEcell counts-BAL cell celularity,UH-Cellularity-BAL cell celularity,UHcell counts-BAL cell celularity",	"provider":"FIOH,NRCWE,UH",	"protocol":"BAL cell celularity,Histopathology",	"publicname":"NRCWE#067",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-60a46dd3-af5d-36b1-a961-aa3a38c312a8",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.3.1. Skin irritation / Corrosion",	"endpoint":"TO_SKIN_IRRITATION_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_SKIN_IRRITATION_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-60a46dd3-af5d-36b1-a961-aa3a38c312a8/study?top=TOX",	"substance":"Porous Silica 100nm-Me",	"reference":"GAIKER_Nanoreg2_Calibrate_template irritation assays_BATCH1",	"provider":"GAIKER",	"protocol":"OECD 439,OECD 492",	"publicname":"NRCWE#067",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-60a46dd3-af5d-36b1-a961-aa3a38c312a8",	"substance_owner":"caLIBRAte"	},
	{
	"value":"4.1. Appearance",	"endpoint":"GI_GENERAL_INFORM_SECTION",
	"count":1,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=GI_GENERAL_INFORM_SECTION",
	"subcategory":"P-CHEM",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-421cd786-8502-3ba5-bf85-548c33053eb9/study?top=P-CHEM",	"substance":"Non-porous Silica 100nm-Me",	"reference":"caLIBRAte",	"provider":"H2020 Calibrate",	"protocol":"",	"publicname":"NRCWE#068",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-421cd786-8502-3ba5-bf85-548c33053eb9",	"substance_owner":"caLIBRAte"	},
	{
	"value":"4.5. Particle size distribution (Granulometry)",	"endpoint":"PC_GRANULOMETRY_SECTION",
	"count":62,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=PC_GRANULOMETRY_SECTION",
	"subcategory":"P-CHEM",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-421cd786-8502-3ba5-bf85-548c33053eb9/study?top=P-CHEM",	"substance":"Non-porous Silica 100nm-Me",	"reference":",FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1,FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1 Sheet: Micronuclei,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Blood biochemistry,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Body&organ weight,LEITAT_FIOH_oral toxicity_FINAL.xlsx#COMET-Local genotoxicity,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Hematological parameters,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Histopathology,NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#Histopathology,NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#mRNA expression in vivo,NRCWE_in_vivo_genotoxic_FINAL.xlsx#COMET",	"provider":"FIOH,NRCWE",	"protocol":"DLS,TEM",	"publicname":"NRCWE#068",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-421cd786-8502-3ba5-bf85-548c33053eb9",	"substance_owner":"caLIBRAte"	},
	{
	"value":"ENM_0000068. Cell Viability",	"endpoint":"ENM_0000068_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=ENM_0000068_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-421cd786-8502-3ba5-bf85-548c33053eb9/study?top=TOX",	"substance":"Non-porous Silica 100nm-Me",	"reference":"Calibrate D5.6",	"provider":"MISVIK",	"protocol":"CellTiter-Glo (CTG)",	"publicname":"NRCWE#068",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-421cd786-8502-3ba5-bf85-548c33053eb9",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.2.2. Acute toxicity - inhalation",	"endpoint":"TO_ACUTE_INHAL_SECTION",
	"count":7,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_ACUTE_INHAL_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-421cd786-8502-3ba5-bf85-548c33053eb9/study?top=TOX",	"substance":"Non-porous Silica 100nm-Me",	"reference":"NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#Histopathology,NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#mRNA expression in vivo",	"provider":"FIOH",	"protocol":"pulmonary toxicity-Histopathology,pulmonary toxicity-Quantitative PCR",	"publicname":"NRCWE#068",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-421cd786-8502-3ba5-bf85-548c33053eb9",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.2.1. Acute toxicity - oral",	"endpoint":"TO_ACUTE_ORAL_SECTION",
	"count":41,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_ACUTE_ORAL_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-421cd786-8502-3ba5-bf85-548c33053eb9/study?top=TOX",	"substance":"Non-porous Silica 100nm-Me",	"reference":"LEITAT_FIOH_oral toxicity_FINAL.xlsx#Blood biochemistry,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Body&organ weight,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Hematological parameters,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Histopathology",	"provider":"LEITAT",	"protocol":"Short term oral toxicity",	"publicname":"NRCWE#068",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-421cd786-8502-3ba5-bf85-548c33053eb9",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.6.2. Genetic toxicity in vivo",	"endpoint":"TO_GENETIC_IN_VIVO_SECTION",
	"count":13,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_GENETIC_IN_VIVO_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-421cd786-8502-3ba5-bf85-548c33053eb9/study?top=TOX",	"substance":"Non-porous Silica 100nm-Me",	"reference":"FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1,FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1 Sheet: Micronuclei,LEITAT_FIOH_oral toxicity_FINAL.xlsx#COMET-Local genotoxicity,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Hyperspectral analysis,NRCWE_in_vivo_genotoxic_FINAL.xlsx#COMET",	"provider":"FIOH,LEITAT,NRCWE",	"protocol":"COMET,Gamma-H2AX,NM detection in intestinal tissue-Hyperspectral image analysis,OECD TG 474,in vivo Comet assay",	"publicname":"NRCWE#068",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-421cd786-8502-3ba5-bf85-548c33053eb9",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.5.2. Repeated dose toxicity - inhalation",	"endpoint":"TO_REPEATED_INHAL_SECTION",
	"count":11,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_REPEATED_INHAL_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-421cd786-8502-3ba5-bf85-548c33053eb9/study?top=TOX",	"substance":"Non-porous Silica 100nm-Me",	"reference":",NRCWE-Cellularity-BAL cell celularity,NRCWEcell counts-BAL cell celularity,UH-Cellularity-BAL cell celularity,UHcell counts-BAL cell celularity",	"provider":"FIOH,NRCWE,UH",	"protocol":"BAL cell celularity,Histopathology",	"publicname":"NRCWE#068",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-421cd786-8502-3ba5-bf85-548c33053eb9",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.3.1. Skin irritation / Corrosion",	"endpoint":"TO_SKIN_IRRITATION_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_SKIN_IRRITATION_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-421cd786-8502-3ba5-bf85-548c33053eb9/study?top=TOX",	"substance":"Non-porous Silica 100nm-Me",	"reference":"GAIKER_Nanoreg2_Calibrate_template irritation assays_BATCH1",	"provider":"GAIKER",	"protocol":"OECD 439,OECD 492",	"publicname":"NRCWE#068",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-421cd786-8502-3ba5-bf85-548c33053eb9",	"substance_owner":"caLIBRAte"	},
	{
	"value":"6.1.1. Short-term toxicity to fish",	"endpoint":"EC_FISHTOX_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=EC_FISHTOX_SECTION",
	"subcategory":"ECOTOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-c2b505cd-36e1-31b5-9303-bbc040f4bdac/study?top=ECOTOX",	"substance":"Porous Silica 300nm-CuO doping-me",	"reference":"Eawag-fish-zFET",	"provider":"EAWAG",	"protocol":"!!! SOP MISSING !!!",	"publicname":"NRCWE#069",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-c2b505cd-36e1-31b5-9303-bbc040f4bdac",	"substance_owner":"caLIBRAte"	},
	{
	"value":"6.3.4. Toxicity to soil microorganisms",	"endpoint":"EC_SOIL_MICRO_TOX_SECTION",
	"count":1,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=EC_SOIL_MICRO_TOX_SECTION",
	"subcategory":"ECOTOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-c2b505cd-36e1-31b5-9303-bbc040f4bdac/study?top=ECOTOX",	"substance":"Porous Silica 300nm-CuO doping-me",	"reference":"NERC environmental toxicity template for FINAL.xlsx",	"provider":"NERC",	"protocol":"OECD 222",	"publicname":"NRCWE#069",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-c2b505cd-36e1-31b5-9303-bbc040f4bdac",	"substance_owner":"caLIBRAte"	},
	{
	"value":"4.1. Appearance",	"endpoint":"GI_GENERAL_INFORM_SECTION",
	"count":1,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=GI_GENERAL_INFORM_SECTION",
	"subcategory":"P-CHEM",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-c2b505cd-36e1-31b5-9303-bbc040f4bdac/study?top=P-CHEM",	"substance":"Porous Silica 300nm-CuO doping-me",	"reference":"caLIBRAte",	"provider":"H2020 Calibrate",	"protocol":"",	"publicname":"NRCWE#069",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-c2b505cd-36e1-31b5-9303-bbc040f4bdac",	"substance_owner":"caLIBRAte"	},
	{
	"value":"4.5. Particle size distribution (Granulometry)",	"endpoint":"PC_GRANULOMETRY_SECTION",
	"count":17,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=PC_GRANULOMETRY_SECTION",
	"subcategory":"P-CHEM",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-c2b505cd-36e1-31b5-9303-bbc040f4bdac/study?top=P-CHEM",	"substance":"Porous Silica 300nm-CuO doping-me",	"reference":",FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1,FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1 Sheet: Micronuclei,NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#Histopathology,NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#mRNA expression in vivo,NRCWE_in_vivo_genotoxic_FINAL.xlsx#COMET,OECD 222",	"provider":"FIOH,NERC,NRCWE",	"protocol":"DLS",	"publicname":"NRCWE#069",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-c2b505cd-36e1-31b5-9303-bbc040f4bdac",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.2.2. Acute toxicity - inhalation",	"endpoint":"TO_ACUTE_INHAL_SECTION",
	"count":7,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_ACUTE_INHAL_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-c2b505cd-36e1-31b5-9303-bbc040f4bdac/study?top=TOX",	"substance":"Porous Silica 300nm-CuO doping-me",	"reference":"NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#Histopathology,NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#mRNA expression in vivo",	"provider":"FIOH",	"protocol":"pulmonary toxicity-Histopathology,pulmonary toxicity-Quantitative PCR",	"publicname":"NRCWE#069",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-c2b505cd-36e1-31b5-9303-bbc040f4bdac",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.6.2. Genetic toxicity in vivo",	"endpoint":"TO_GENETIC_IN_VIVO_SECTION",
	"count":8,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_GENETIC_IN_VIVO_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-c2b505cd-36e1-31b5-9303-bbc040f4bdac/study?top=TOX",	"substance":"Porous Silica 300nm-CuO doping-me",	"reference":"FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1,FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1 Sheet: Micronuclei,NRCWE_in_vivo_genotoxic_FINAL.xlsx#COMET",	"provider":"FIOH,NRCWE",	"protocol":"COMET,Gamma-H2AX,OECD TG 474",	"publicname":"NRCWE#069",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-c2b505cd-36e1-31b5-9303-bbc040f4bdac",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.5.2. Repeated dose toxicity - inhalation",	"endpoint":"TO_REPEATED_INHAL_SECTION",
	"count":5,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_REPEATED_INHAL_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-c2b505cd-36e1-31b5-9303-bbc040f4bdac/study?top=TOX",	"substance":"Porous Silica 300nm-CuO doping-me",	"reference":",NRCWE-Cellularity-BAL cell celularity,NRCWEcell counts-BAL cell celularity",	"provider":"FIOH,NRCWE",	"protocol":"BAL cell celularity,Histopathology",	"publicname":"NRCWE#069",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-c2b505cd-36e1-31b5-9303-bbc040f4bdac",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.3.1. Skin irritation / Corrosion",	"endpoint":"TO_SKIN_IRRITATION_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_SKIN_IRRITATION_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-c2b505cd-36e1-31b5-9303-bbc040f4bdac/study?top=TOX",	"substance":"Porous Silica 300nm-CuO doping-me",	"reference":"GAIKER_Nanoreg2_Calibrate_template irritation assays_BATCH1",	"provider":"GAIKER",	"protocol":"OECD 439,OECD 492",	"publicname":"NRCWE#069",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-c2b505cd-36e1-31b5-9303-bbc040f4bdac",	"substance_owner":"caLIBRAte"	},
	{
	"value":"6.1.1. Short-term toxicity to fish",	"endpoint":"EC_FISHTOX_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=EC_FISHTOX_SECTION",
	"subcategory":"ECOTOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-1f64690a-29cd-33ac-905f-2c9f866f4bf2/study?top=ECOTOX",	"substance":"Porous Silica 100nm-CuO doping-me",	"reference":"Eawag-fish-zFET",	"provider":"EAWAG",	"protocol":"!!! SOP MISSING !!!",	"publicname":"NRCWE#070",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-1f64690a-29cd-33ac-905f-2c9f866f4bf2",	"substance_owner":"caLIBRAte"	},
	{
	"value":"4.1. Appearance",	"endpoint":"GI_GENERAL_INFORM_SECTION",
	"count":1,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=GI_GENERAL_INFORM_SECTION",
	"subcategory":"P-CHEM",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-1f64690a-29cd-33ac-905f-2c9f866f4bf2/study?top=P-CHEM",	"substance":"Porous Silica 100nm-CuO doping-me",	"reference":"caLIBRAte",	"provider":"H2020 Calibrate",	"protocol":"",	"publicname":"NRCWE#070",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-1f64690a-29cd-33ac-905f-2c9f866f4bf2",	"substance_owner":"caLIBRAte"	},
	{
	"value":"4.5. Particle size distribution (Granulometry)",	"endpoint":"PC_GRANULOMETRY_SECTION",
	"count":16,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=PC_GRANULOMETRY_SECTION",
	"subcategory":"P-CHEM",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-1f64690a-29cd-33ac-905f-2c9f866f4bf2/study?top=P-CHEM",	"substance":"Porous Silica 100nm-CuO doping-me",	"reference":",FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1,FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1 Sheet: Micronuclei,NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#Histopathology,NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#mRNA expression in vivo,NRCWE_in_vivo_genotoxic_FINAL.xlsx#COMET",	"provider":"FIOH,NRCWE",	"protocol":"DLS",	"publicname":"NRCWE#070",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-1f64690a-29cd-33ac-905f-2c9f866f4bf2",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.2.2. Acute toxicity - inhalation",	"endpoint":"TO_ACUTE_INHAL_SECTION",
	"count":7,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_ACUTE_INHAL_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-1f64690a-29cd-33ac-905f-2c9f866f4bf2/study?top=TOX",	"substance":"Porous Silica 100nm-CuO doping-me",	"reference":"NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#Histopathology,NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#mRNA expression in vivo",	"provider":"FIOH",	"protocol":"pulmonary toxicity-Histopathology,pulmonary toxicity-Quantitative PCR",	"publicname":"NRCWE#070",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-1f64690a-29cd-33ac-905f-2c9f866f4bf2",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.6.2. Genetic toxicity in vivo",	"endpoint":"TO_GENETIC_IN_VIVO_SECTION",
	"count":8,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_GENETIC_IN_VIVO_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-1f64690a-29cd-33ac-905f-2c9f866f4bf2/study?top=TOX",	"substance":"Porous Silica 100nm-CuO doping-me",	"reference":"FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1,FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1 Sheet: Micronuclei,NRCWE_in_vivo_genotoxic_FINAL.xlsx#COMET",	"provider":"FIOH,NRCWE",	"protocol":"COMET,Gamma-H2AX,OECD TG 474",	"publicname":"NRCWE#070",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-1f64690a-29cd-33ac-905f-2c9f866f4bf2",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.5.2. Repeated dose toxicity - inhalation",	"endpoint":"TO_REPEATED_INHAL_SECTION",
	"count":5,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_REPEATED_INHAL_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-1f64690a-29cd-33ac-905f-2c9f866f4bf2/study?top=TOX",	"substance":"Porous Silica 100nm-CuO doping-me",	"reference":",NRCWE-Cellularity-BAL cell celularity,NRCWEcell counts-BAL cell celularity",	"provider":"FIOH,NRCWE",	"protocol":"BAL cell celularity,Histopathology",	"publicname":"NRCWE#070",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-1f64690a-29cd-33ac-905f-2c9f866f4bf2",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.3.1. Skin irritation / Corrosion",	"endpoint":"TO_SKIN_IRRITATION_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_SKIN_IRRITATION_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-1f64690a-29cd-33ac-905f-2c9f866f4bf2/study?top=TOX",	"substance":"Porous Silica 100nm-CuO doping-me",	"reference":"GAIKER_Nanoreg2_Calibrate_template irritation assays_BATCH1",	"provider":"GAIKER",	"protocol":"OECD 439,OECD 492",	"publicname":"NRCWE#070",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-1f64690a-29cd-33ac-905f-2c9f866f4bf2",	"substance_owner":"caLIBRAte"	},
	{
	"value":"6.1.1. Short-term toxicity to fish",	"endpoint":"EC_FISHTOX_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=EC_FISHTOX_SECTION",
	"subcategory":"ECOTOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-98cf6892-a120-386b-82c4-c4658e3a84b1/study?top=ECOTOX",	"substance":"Non-porous Silica 300nm-CuO doping-me",	"reference":"Eawag-fish-zFET",	"provider":"EAWAG",	"protocol":"!!! SOP MISSING !!!",	"publicname":"NRCWE#071",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-98cf6892-a120-386b-82c4-c4658e3a84b1",	"substance_owner":"caLIBRAte"	},
	{
	"value":"4.1. Appearance",	"endpoint":"GI_GENERAL_INFORM_SECTION",
	"count":1,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=GI_GENERAL_INFORM_SECTION",
	"subcategory":"P-CHEM",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-98cf6892-a120-386b-82c4-c4658e3a84b1/study?top=P-CHEM",	"substance":"Non-porous Silica 300nm-CuO doping-me",	"reference":"caLIBRAte",	"provider":"H2020 Calibrate",	"protocol":"",	"publicname":"NRCWE#071",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-98cf6892-a120-386b-82c4-c4658e3a84b1",	"substance_owner":"caLIBRAte"	},
	{
	"value":"4.5. Particle size distribution (Granulometry)",	"endpoint":"PC_GRANULOMETRY_SECTION",
	"count":16,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=PC_GRANULOMETRY_SECTION",
	"subcategory":"P-CHEM",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-98cf6892-a120-386b-82c4-c4658e3a84b1/study?top=P-CHEM",	"substance":"Non-porous Silica 300nm-CuO doping-me",	"reference":",FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1,FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1 Sheet: Micronuclei,NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#Histopathology,NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#mRNA expression in vivo,NRCWE_in_vivo_genotoxic_FINAL.xlsx#COMET",	"provider":"FIOH,NRCWE",	"protocol":"DLS",	"publicname":"NRCWE#071",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-98cf6892-a120-386b-82c4-c4658e3a84b1",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.2.2. Acute toxicity - inhalation",	"endpoint":"TO_ACUTE_INHAL_SECTION",
	"count":7,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_ACUTE_INHAL_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-98cf6892-a120-386b-82c4-c4658e3a84b1/study?top=TOX",	"substance":"Non-porous Silica 300nm-CuO doping-me",	"reference":"NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#Histopathology,NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#mRNA expression in vivo",	"provider":"FIOH",	"protocol":"pulmonary toxicity-Histopathology,pulmonary toxicity-Quantitative PCR",	"publicname":"NRCWE#071",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-98cf6892-a120-386b-82c4-c4658e3a84b1",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.6.2. Genetic toxicity in vivo",	"endpoint":"TO_GENETIC_IN_VIVO_SECTION",
	"count":8,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_GENETIC_IN_VIVO_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-98cf6892-a120-386b-82c4-c4658e3a84b1/study?top=TOX",	"substance":"Non-porous Silica 300nm-CuO doping-me",	"reference":"FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1,FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1 Sheet: Micronuclei,NRCWE_in_vivo_genotoxic_FINAL.xlsx#COMET",	"provider":"FIOH,NRCWE",	"protocol":"COMET,Gamma-H2AX,OECD TG 474",	"publicname":"NRCWE#071",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-98cf6892-a120-386b-82c4-c4658e3a84b1",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.5.2. Repeated dose toxicity - inhalation",	"endpoint":"TO_REPEATED_INHAL_SECTION",
	"count":5,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_REPEATED_INHAL_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-98cf6892-a120-386b-82c4-c4658e3a84b1/study?top=TOX",	"substance":"Non-porous Silica 300nm-CuO doping-me",	"reference":",NRCWE-Cellularity-BAL cell celularity,NRCWEcell counts-BAL cell celularity",	"provider":"FIOH,NRCWE",	"protocol":"BAL cell celularity,Histopathology",	"publicname":"NRCWE#071",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-98cf6892-a120-386b-82c4-c4658e3a84b1",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.3.1. Skin irritation / Corrosion",	"endpoint":"TO_SKIN_IRRITATION_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_SKIN_IRRITATION_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-98cf6892-a120-386b-82c4-c4658e3a84b1/study?top=TOX",	"substance":"Non-porous Silica 300nm-CuO doping-me",	"reference":"GAIKER_Nanoreg2_Calibrate_template irritation assays_BATCH1",	"provider":"GAIKER",	"protocol":"OECD 439,OECD 492",	"publicname":"NRCWE#071",	"substancetype":"NPO_1373",	"substance_uuid":"CLBR-98cf6892-a120-386b-82c4-c4658e3a84b1",	"substance_owner":"caLIBRAte"	},
	{
	"value":"6.1.1. Short-term toxicity to fish",	"endpoint":"EC_FISHTOX_SECTION",
	"count":3,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=EC_FISHTOX_SECTION",
	"subcategory":"ECOTOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-31b81873-9aeb-3a4f-b546-31f1c33f80dc/study?top=ECOTOX",	"substance":"CuO nanoparticles",	"reference":"Eawag-fish-OECD; Fish Embryo Acute Toxicity (FET) Test",	"provider":"EAWAG",	"protocol":"OECD 236: Fish Embryo Acute Toxicity (FET) Test",	"publicname":"NRCWE#072",	"substancetype":"NPO_1544",	"substance_uuid":"CLBR-31b81873-9aeb-3a4f-b546-31f1c33f80dc",	"substance_owner":"caLIBRAte"	},
	{
	"value":"6.3.4. Toxicity to soil microorganisms",	"endpoint":"EC_SOIL_MICRO_TOX_SECTION",
	"count":1,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=EC_SOIL_MICRO_TOX_SECTION",
	"subcategory":"ECOTOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-31b81873-9aeb-3a4f-b546-31f1c33f80dc/study?top=ECOTOX",	"substance":"CuO nanoparticles",	"reference":"NERC environmental toxicity template for FINAL.xlsx",	"provider":"NERC",	"protocol":"OECD 222",	"publicname":"NRCWE#072",	"substancetype":"NPO_1544",	"substance_uuid":"CLBR-31b81873-9aeb-3a4f-b546-31f1c33f80dc",	"substance_owner":"caLIBRAte"	},
	{
	"value":"4.1. Appearance",	"endpoint":"GI_GENERAL_INFORM_SECTION",
	"count":1,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=GI_GENERAL_INFORM_SECTION",
	"subcategory":"P-CHEM",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-31b81873-9aeb-3a4f-b546-31f1c33f80dc/study?top=P-CHEM",	"substance":"CuO nanoparticles",	"reference":"caLIBRAte",	"provider":"H2020 Calibrate",	"protocol":"",	"publicname":"NRCWE#072",	"substancetype":"NPO_1544",	"substance_uuid":"CLBR-31b81873-9aeb-3a4f-b546-31f1c33f80dc",	"substance_owner":"caLIBRAte"	},
	{
	"value":"4.5. Particle size distribution (Granulometry)",	"endpoint":"PC_GRANULOMETRY_SECTION",
	"count":20,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=PC_GRANULOMETRY_SECTION",
	"subcategory":"P-CHEM",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-31b81873-9aeb-3a4f-b546-31f1c33f80dc/study?top=P-CHEM",	"substance":"CuO nanoparticles",	"reference":",EAWAG_Nanoreg _template_Environmental_Toxicity_EAWAG_BATCH1 Sheet: water-fish-DRerio,FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1,FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1 Sheet: Micronuclei,NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#Histopathology,NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#mRNA expression in vivo,NRCWE_in_vivo_genotoxic_FINAL.xlsx#COMET,OECD 222",	"provider":"EAWAG,FIOH,NERC,NRCWE",	"protocol":"DLS",	"publicname":"NRCWE#072",	"substancetype":"NPO_1544",	"substance_uuid":"CLBR-31b81873-9aeb-3a4f-b546-31f1c33f80dc",	"substance_owner":"caLIBRAte"	},
	{
	"value":"ENM_0000068. Cell Viability",	"endpoint":"ENM_0000068_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=ENM_0000068_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-31b81873-9aeb-3a4f-b546-31f1c33f80dc/study?top=TOX",	"substance":"CuO nanoparticles",	"reference":"Calibrate D5.6",	"provider":"MISVIK",	"protocol":"CellTiter-Glo (CTG)",	"publicname":"NRCWE#072",	"substancetype":"NPO_1544",	"substance_uuid":"CLBR-31b81873-9aeb-3a4f-b546-31f1c33f80dc",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.2.2. Acute toxicity - inhalation",	"endpoint":"TO_ACUTE_INHAL_SECTION",
	"count":7,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_ACUTE_INHAL_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-31b81873-9aeb-3a4f-b546-31f1c33f80dc/study?top=TOX",	"substance":"CuO nanoparticles",	"reference":"NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#Histopathology,NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#mRNA expression in vivo",	"provider":"FIOH",	"protocol":"pulmonary toxicity-Histopathology,pulmonary toxicity-Quantitative PCR",	"publicname":"NRCWE#072",	"substancetype":"NPO_1544",	"substance_uuid":"CLBR-31b81873-9aeb-3a4f-b546-31f1c33f80dc",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.6.2. Genetic toxicity in vivo",	"endpoint":"TO_GENETIC_IN_VIVO_SECTION",
	"count":8,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_GENETIC_IN_VIVO_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-31b81873-9aeb-3a4f-b546-31f1c33f80dc/study?top=TOX",	"substance":"CuO nanoparticles",	"reference":"FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1,FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1 Sheet: Micronuclei,NRCWE_in_vivo_genotoxic_FINAL.xlsx#COMET",	"provider":"FIOH,NRCWE",	"protocol":"COMET,Gamma-H2AX,OECD TG 474",	"publicname":"NRCWE#072",	"substancetype":"NPO_1544",	"substance_uuid":"CLBR-31b81873-9aeb-3a4f-b546-31f1c33f80dc",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.5.2. Repeated dose toxicity - inhalation",	"endpoint":"TO_REPEATED_INHAL_SECTION",
	"count":5,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_REPEATED_INHAL_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-31b81873-9aeb-3a4f-b546-31f1c33f80dc/study?top=TOX",	"substance":"CuO nanoparticles",	"reference":",NRCWE-Cellularity-BAL cell celularity,NRCWEcell counts-BAL cell celularity",	"provider":"FIOH,NRCWE",	"protocol":"BAL cell celularity,Histopathology",	"publicname":"NRCWE#072",	"substancetype":"NPO_1544",	"substance_uuid":"CLBR-31b81873-9aeb-3a4f-b546-31f1c33f80dc",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.3.1. Skin irritation / Corrosion",	"endpoint":"TO_SKIN_IRRITATION_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_SKIN_IRRITATION_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-31b81873-9aeb-3a4f-b546-31f1c33f80dc/study?top=TOX",	"substance":"CuO nanoparticles",	"reference":"GAIKER_Nanoreg2_Calibrate_template irritation assays_BATCH1",	"provider":"GAIKER",	"protocol":"OECD 439,OECD 492",	"publicname":"NRCWE#072",	"substancetype":"NPO_1544",	"substance_uuid":"CLBR-31b81873-9aeb-3a4f-b546-31f1c33f80dc",	"substance_owner":"caLIBRAte"	},
	{
	"value":"4.1. Appearance",	"endpoint":"GI_GENERAL_INFORM_SECTION",
	"count":1,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=GI_GENERAL_INFORM_SECTION",
	"subcategory":"P-CHEM",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-49757af6-7d87-3473-9a74-ce5ffb40f9e2/study?top=P-CHEM",	"substance":"printex 90",	"reference":"caLIBRAte",	"provider":"H2020 Calibrate",	"protocol":"",	"publicname":"PRINTEX 90",	"substancetype":"CHEBI_82297",	"substance_uuid":"CLBR-49757af6-7d87-3473-9a74-ce5ffb40f9e2",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.2.2. Acute toxicity - inhalation",	"endpoint":"TO_ACUTE_INHAL_SECTION",
	"count":3,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_ACUTE_INHAL_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-49757af6-7d87-3473-9a74-ce5ffb40f9e2/study?top=TOX",	"substance":"printex 90",	"reference":"NRCWE_FIOH_biol_effects_pul_dep_FINAL.xlsx#mRNA expression in vivo",	"provider":"FIOH",	"protocol":"pulmonary toxicity-Quantitative PCR",	"publicname":"PRINTEX 90",	"substancetype":"CHEBI_82297",	"substance_uuid":"CLBR-49757af6-7d87-3473-9a74-ce5ffb40f9e2",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.6.2. Genetic toxicity in vivo",	"endpoint":"TO_GENETIC_IN_VIVO_SECTION",
	"count":7,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_GENETIC_IN_VIVO_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-49757af6-7d87-3473-9a74-ce5ffb40f9e2/study?top=TOX",	"substance":"printex 90",	"reference":"FIOH In_vivo_toxicity_NIH18-01_MNi_Gamma_Histopathology_FIOH_BATCH1 Sheet: Micronuclei,NRCWE_in_vivo_genotoxic_FINAL.xlsx#COMET",	"provider":"FIOH,NRCWE",	"protocol":"COMET,OECD TG 474",	"publicname":"PRINTEX 90",	"substancetype":"CHEBI_82297",	"substance_uuid":"CLBR-49757af6-7d87-3473-9a74-ce5ffb40f9e2",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.5.2. Repeated dose toxicity - inhalation",	"endpoint":"TO_REPEATED_INHAL_SECTION",
	"count":8,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_REPEATED_INHAL_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-49757af6-7d87-3473-9a74-ce5ffb40f9e2/study?top=TOX",	"substance":"printex 90",	"reference":"NRCWE-Cellularity-BAL cell celularity,NRCWEcell counts-BAL cell celularity,UH-Cellularity-BAL cell celularity,UHcell counts-BAL cell celularity",	"provider":"NRCWE,UH",	"protocol":"BAL cell celularity",	"publicname":"PRINTEX 90",	"substancetype":"CHEBI_82297",	"substance_uuid":"CLBR-49757af6-7d87-3473-9a74-ce5ffb40f9e2",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.2.1. Acute toxicity - oral",	"endpoint":"TO_ACUTE_ORAL_SECTION",
	"count":42,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_ACUTE_ORAL_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-1710e876-d940-3da7-86dd-e84acfa6908d/study?top=TOX",	"substance":"0.2% (w/v) CMC  + 1% (v/v) Tween80 in MiliQ water ",	"reference":"LEITAT_FIOH_oral toxicity_FINAL.xlsx#Blood biochemistry,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Body&organ weight,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Hematological parameters,LEITAT_FIOH_oral toxicity_FINAL.xlsx#Histopathology",	"provider":"LEITAT",	"protocol":"Short term oral toxicity",	"publicname":"0.2% (W/V) CMC  + 1% (V/V) TWEEN80 IN MILIQ WATER",	"substancetype":null,	"substance_uuid":"CLBR-1710e876-d940-3da7-86dd-e84acfa6908d",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.6.2. Genetic toxicity in vivo",	"endpoint":"TO_GENETIC_IN_VIVO_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_GENETIC_IN_VIVO_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-1710e876-d940-3da7-86dd-e84acfa6908d/study?top=TOX",	"substance":"0.2% (w/v) CMC  + 1% (v/v) Tween80 in MiliQ water ",	"reference":"LEITAT_FIOH_oral toxicity_FINAL.xlsx#COMET-Local genotoxicity",	"provider":"LEITAT",	"protocol":"in vivo Comet assay",	"publicname":"0.2% (W/V) CMC  + 1% (V/V) TWEEN80 IN MILIQ WATER",	"substancetype":null,	"substance_uuid":"CLBR-1710e876-d940-3da7-86dd-e84acfa6908d",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.6.2. Genetic toxicity in vivo",	"endpoint":"TO_GENETIC_IN_VIVO_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_GENETIC_IN_VIVO_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-db9f01dc-c852-356d-9f5e-b514150f38fa/study?top=TOX",	"substance":"0.9% NaCl (w/v) in MiliQ water ",	"reference":"LEITAT_FIOH_oral toxicity_FINAL.xlsx#COMET-Local genotoxicity",	"provider":"LEITAT",	"protocol":"OECD TG 474",	"publicname":"0.9% NACL (W/V) IN MILIQ WATER",	"substancetype":"CHEBI_59999",	"substance_uuid":"CLBR-db9f01dc-c852-356d-9f5e-b514150f38fa",	"substance_owner":"caLIBRAte"	},
	{
	"value":"7.6.2. Genetic toxicity in vivo",	"endpoint":"TO_GENETIC_IN_VIVO_SECTION",
	"count":4,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=TO_GENETIC_IN_VIVO_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-68ef4276-65b8-3087-9008-0563e89ade9b/study?top=TOX",	"substance":"MMS",	"reference":"LEITAT_FIOH_oral toxicity_FINAL.xlsx#COMET-Local genotoxicity",	"provider":"LEITAT",	"protocol":"OECD TG 474,in vivo Comet assay",	"publicname":"Methylmethane sulfonate",	"substancetype":"CHEBI_59999",	"substance_uuid":"CLBR-68ef4276-65b8-3087-9008-0563e89ade9b",	"substance_owner":"caLIBRAte"	},
	{
	"value":"6.3.4. Toxicity to soil microorganisms",	"endpoint":"EC_SOIL_MICRO_TOX_SECTION",
	"count":4,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=EC_SOIL_MICRO_TOX_SECTION",
	"subcategory":"ECOTOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-7dba0244-884f-3d36-96e8-b066c0cca496/study?top=ECOTOX",	"substance":"control_NERC",	"reference":"NERC environmental toxicity template for FINAL.xlsx",	"provider":"NERC",	"protocol":"OECD 222",	"publicname":"CONTROL_NERC",	"substancetype":null,	"substance_uuid":"CLBR-7dba0244-884f-3d36-96e8-b066c0cca496",	"substance_owner":"caLIBRAte"	},
	{
	"value":"6.3.4. Toxicity to soil microorganisms",	"endpoint":"EC_SOIL_MICRO_TOX_SECTION",
	"count":1,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=EC_SOIL_MICRO_TOX_SECTION",
	"subcategory":"ECOTOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-09dbacf5-be75-3508-96a4-4aa1509f37e8/study?top=ECOTOX",	"substance":"Copper dinitrate",	"reference":"NERC environmental toxicity template for FINAL.xlsx",	"provider":"NERC",	"protocol":"OECD 222",	"publicname":"3251-23-8",	"substancetype":null,	"substance_uuid":"CLBR-09dbacf5-be75-3508-96a4-4aa1509f37e8",	"substance_owner":"caLIBRAte"	},
	{
	"value":"4.1. Appearance",	"endpoint":"GI_GENERAL_INFORM_SECTION",
	"count":1,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=GI_GENERAL_INFORM_SECTION",
	"subcategory":"P-CHEM",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-09dbacf5-be75-3508-96a4-4aa1509f37e8/study?top=P-CHEM",	"substance":"Copper dinitrate",	"reference":"caLIBRAte",	"provider":"H2020 Calibrate",	"protocol":"",	"publicname":"3251-23-8",	"substancetype":null,	"substance_uuid":"CLBR-09dbacf5-be75-3508-96a4-4aa1509f37e8",	"substance_owner":"caLIBRAte"	},
	{
	"value":"ENM_0000068. Cell Viability",	"endpoint":"ENM_0000068_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=ENM_0000068_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-903711f1-4144-3761-acdf-cb12c268e856/study?top=TOX",	"substance":"Titanium(IV)oxide",	"reference":"Calibrate D5.6",	"provider":"MISVIK",	"protocol":"CellTiter-Glo (CTG)",	"publicname":"TIOXIDE TR81",	"substancetype":null,	"substance_uuid":"CLBR-903711f1-4144-3761-acdf-cb12c268e856",	"substance_owner":"caLIBRAte"	},
	{
	"value":"ENM_0000068. Cell Viability",	"endpoint":"ENM_0000068_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=ENM_0000068_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-d0a56d49-8e19-3c1a-a5a6-fb2e924699f3/study?top=TOX",	"substance":"Dolomite",	"reference":"Calibrate D5.6",	"provider":"MISVIK",	"protocol":"CellTiter-Glo (CTG)",	"publicname":"MICRODOL",	"substancetype":null,	"substance_uuid":"CLBR-d0a56d49-8e19-3c1a-a5a6-fb2e924699f3",	"substance_owner":"caLIBRAte"	},
	{
	"value":"ENM_0000068. Cell Viability",	"endpoint":"ENM_0000068_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=ENM_0000068_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-68591325-d7b4-3e13-b614-ad625412e9f3/study?top=TOX",	"substance":"Talcum",	"reference":"Calibrate D5.6",	"provider":"MISVIK",	"protocol":"CellTiter-Glo (CTG)",	"publicname":"FINNTALC M15",	"substancetype":null,	"substance_uuid":"CLBR-68591325-d7b4-3e13-b614-ad625412e9f3",	"substance_owner":"caLIBRAte"	},
	{
	"value":"ENM_0000068. Cell Viability",	"endpoint":"ENM_0000068_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=ENM_0000068_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-9c277ff8-238d-3964-8347-71e6efd4c0d3/study?top=TOX",	"substance":"calcined kaolin",	"reference":"Calibrate D5.6",	"provider":"MISVIK",	"protocol":"CellTiter-Glo (CTG)",	"publicname":"POLESTAR™ 200P",	"substancetype":null,	"substance_uuid":"CLBR-9c277ff8-238d-3964-8347-71e6efd4c0d3",	"substance_owner":"caLIBRAte"	},
	{
	"value":"ENM_0000068. Cell Viability",	"endpoint":"ENM_0000068_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=ENM_0000068_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-f8a7923c-4251-3756-8652-07f56c17467a/study?top=TOX",	"substance":"Calcium Carbonate",	"reference":"Calibrate D5.6",	"provider":"MISVIK",	"protocol":"CellTiter-Glo (CTG)",	"publicname":"SOCAL® P2 FINE GRADES",	"substancetype":null,	"substance_uuid":"CLBR-f8a7923c-4251-3756-8652-07f56c17467a",	"substance_owner":"caLIBRAte"	},
	{
	"value":"ENM_0000068. Cell Viability",	"endpoint":"ENM_0000068_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=ENM_0000068_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-d739f54b-9e07-3a1d-bffd-2665079e4e63/study?top=TOX",	"substance":"Alumino Silica",	"reference":"Calibrate D5.6",	"provider":"MISVIK",	"protocol":"CellTiter-Glo (CTG)",	"publicname":"OPTIMAT® 2550",	"substancetype":null,	"substance_uuid":"CLBR-d739f54b-9e07-3a1d-bffd-2665079e4e63",	"substance_owner":"caLIBRAte"	},
	{
	"value":"ENM_0000068. Cell Viability",	"endpoint":"ENM_0000068_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=ENM_0000068_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-70cf1ff3-2c00-33b2-a41e-0c6531b906a3/study?top=TOX",	"substance":"Expancel",	"reference":"Calibrate D5.6",	"provider":"MISVIK",	"protocol":"CellTiter-Glo (CTG)",	"publicname":"EXPANCEL 461 WE 20 D36",	"substancetype":null,	"substance_uuid":"CLBR-70cf1ff3-2c00-33b2-a41e-0c6531b906a3",	"substance_owner":"caLIBRAte"	},
	{
	"value":"ENM_0000068. Cell Viability",	"endpoint":"ENM_0000068_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=ENM_0000068_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-bd792d96-a553-3b41-97f5-f26e9f65d2c7/study?top=TOX",	"substance":"Sodiumhexametaphosphate",	"reference":"Calibrate D5.6",	"provider":"MISVIK",	"protocol":"CellTiter-Glo (CTG)",	"publicname":"SODIUMHEXAMETAPHOSPHAT PLV",	"substancetype":null,	"substance_uuid":"CLBR-bd792d96-a553-3b41-97f5-f26e9f65d2c7",	"substance_owner":"caLIBRAte"	},
	{
	"value":"ENM_0000068. Cell Viability",	"endpoint":"ENM_0000068_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=ENM_0000068_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-32d3b166-5c75-3a78-9bcb-bbd1ffe03b25/study?top=TOX",	"substance":"2-hydroxyethyl cellulose",	"reference":"Calibrate D5.6",	"provider":"MISVIK",	"protocol":"CellTiter-Glo (CTG)",	"publicname":"TYLOSE HS 6000 YP2",	"substancetype":null,	"substance_uuid":"CLBR-32d3b166-5c75-3a78-9bcb-bbd1ffe03b25",	"substance_owner":"caLIBRAte"	},
	{
	"value":"ENM_0000068. Cell Viability",	"endpoint":"ENM_0000068_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=ENM_0000068_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-cb1cbb79-6e25-331a-8a14-ab727bf74bba/study?top=TOX",	"substance":"tetrapotassium diphosphate",	"reference":"Calibrate D5.6",	"provider":"MISVIK",	"protocol":"CellTiter-Glo (CTG)",	"publicname":"TETRAPOTASSIUMPYROPHOSPHAT PLV",	"substancetype":null,	"substance_uuid":"CLBR-cb1cbb79-6e25-331a-8a14-ab727bf74bba",	"substance_owner":"caLIBRAte"	},
	{
	"value":"ENM_0000068. Cell Viability",	"endpoint":"ENM_0000068_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=ENM_0000068_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-e5ed1d5d-efe2-3526-9e36-1b9137346dbf/study?top=TOX",	"substance":"Porous Silica 300nm-CuO doping-Me",	"reference":"Calibrate D5.6",	"provider":"MISVIK",	"protocol":"CellTiter-Glo (CTG)",	"publicname":"NRCWE#069 ",	"substancetype":null,	"substance_uuid":"CLBR-e5ed1d5d-efe2-3526-9e36-1b9137346dbf",	"substance_owner":"caLIBRAte"	},
	{
	"value":"ENM_0000068. Cell Viability",	"endpoint":"ENM_0000068_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=ENM_0000068_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-6a2c02d1-fee1-39be-af0a-17436a182361/study?top=TOX",	"substance":"Porous Silica 100nm-CuO doping-Me",	"reference":"Calibrate D5.6",	"provider":"MISVIK",	"protocol":"CellTiter-Glo (CTG)",	"publicname":"NRCWE#070 ",	"substancetype":null,	"substance_uuid":"CLBR-6a2c02d1-fee1-39be-af0a-17436a182361",	"substance_owner":"caLIBRAte"	},
	{
	"value":"ENM_0000068. Cell Viability",	"endpoint":"ENM_0000068_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=ENM_0000068_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-c1cf5b87-d758-3eb8-8f55-964a456178e3/study?top=TOX",	"substance":"Non-Porous Silica 300nm-CuO doping-Me",	"reference":"Calibrate D5.6",	"provider":"MISVIK",	"protocol":"CellTiter-Glo (CTG)",	"publicname":"NRCWE#071 ",	"substancetype":null,	"substance_uuid":"CLBR-c1cf5b87-d758-3eb8-8f55-964a456178e3",	"substance_owner":"caLIBRAte"	},
	{
	"value":"ENM_0000068. Cell Viability",	"endpoint":"ENM_0000068_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=ENM_0000068_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-8ce457c0-de68-3ed8-ba2d-77e9bebc7b00/study?top=TOX",	"substance":"A1 Silver nanoparticles",	"reference":"Calibrate D5.6",	"provider":"MISVIK",	"protocol":"CellTiter-Glo (CTG)",	"publicname":"A1 SILVER NANOPARTICLES",	"substancetype":null,	"substance_uuid":"CLBR-8ce457c0-de68-3ed8-ba2d-77e9bebc7b00",	"substance_owner":"caLIBRAte"	},
	{
	"value":"ENM_0000068. Cell Viability",	"endpoint":"ENM_0000068_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=ENM_0000068_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-98c7723a-4deb-3294-a47c-0569dddcaec1/study?top=TOX",	"substance":"A2 Silver nanoparticles (less ions)",	"reference":"Calibrate D5.6",	"provider":"MISVIK",	"protocol":"CellTiter-Glo (CTG)",	"publicname":"A2 SILVER NANOPARTICLES",	"substancetype":null,	"substance_uuid":"CLBR-98c7723a-4deb-3294-a47c-0569dddcaec1",	"substance_owner":"caLIBRAte"	},
	{
	"value":"ENM_0000068. Cell Viability",	"endpoint":"ENM_0000068_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=ENM_0000068_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-b2dfa1bf-ec9e-3602-a278-519fb2cd3ce6/study?top=TOX",	"substance":"Gemcitabine",	"reference":"Calibrate D5.6",	"provider":"MISVIK",	"protocol":"CellTiter-Glo (CTG)",	"publicname":"GEMCITABINE",	"substancetype":null,	"substance_uuid":"CLBR-b2dfa1bf-ec9e-3602-a278-519fb2cd3ce6",	"substance_owner":"caLIBRAte"	},
	{
	"value":"ENM_0000068. Cell Viability",	"endpoint":"ENM_0000068_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=ENM_0000068_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-b153a788-1b51-332d-ab2c-ba55e037b532/study?top=TOX",	"substance":"5-Fluorouracil",	"reference":"Calibrate D5.6",	"provider":"MISVIK",	"protocol":"CellTiter-Glo (CTG)",	"publicname":"5-FU",	"substancetype":null,	"substance_uuid":"CLBR-b153a788-1b51-332d-ab2c-ba55e037b532",	"substance_owner":"caLIBRAte"	},
	{
	"value":"ENM_0000068. Cell Viability",	"endpoint":"ENM_0000068_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=ENM_0000068_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-698880c0-fc78-394b-a5e8-c9c376a8ff92/study?top=TOX",	"substance":"4-Nitroquinoline 1-oxide",	"reference":"Calibrate D5.6",	"provider":"MISVIK",	"protocol":"CellTiter-Glo (CTG)",	"publicname":"4NQO",	"substancetype":null,	"substance_uuid":"CLBR-698880c0-fc78-394b-a5e8-c9c376a8ff92",	"substance_owner":"caLIBRAte"	},
	{
	"value":"ENM_0000068. Cell Viability",	"endpoint":"ENM_0000068_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=ENM_0000068_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-7a5578ad-e0d9-3707-85bf-576505a50354/study?top=TOX",	"substance":"Mitomycin C ",	"reference":"Calibrate D5.6",	"provider":"MISVIK",	"protocol":"CellTiter-Glo (CTG)",	"publicname":"MMC",	"substancetype":"CHEBI_59999",	"substance_uuid":"CLBR-7a5578ad-e0d9-3707-85bf-576505a50354",	"substance_owner":"caLIBRAte"	},
	{
	"value":"ENM_0000068. Cell Viability",	"endpoint":"ENM_0000068_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=ENM_0000068_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-b62644bb-f987-34ab-9fdb-0c794f6a2be6/study?top=TOX",	"substance":"Daunorubicin ",	"reference":"Calibrate D5.6",	"provider":"MISVIK",	"protocol":"CellTiter-Glo (CTG)",	"publicname":"DAUNORUBICIN",	"substancetype":null,	"substance_uuid":"CLBR-b62644bb-f987-34ab-9fdb-0c794f6a2be6",	"substance_owner":"caLIBRAte"	},
	{
	"value":"ENM_0000068. Cell Viability",	"endpoint":"ENM_0000068_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=ENM_0000068_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-695bb838-0eb7-3185-b9ad-1df5ea868bae/study?top=TOX",	"substance":"TiO2",	"reference":"Calibrate D5.6",	"provider":"MISVIK",	"protocol":"CellTiter-Glo (CTG)",	"publicname":"T1 TIO2",	"substancetype":null,	"substance_uuid":"CLBR-695bb838-0eb7-3185-b9ad-1df5ea868bae",	"substance_owner":"caLIBRAte"	},
	{
	"value":"ENM_0000068. Cell Viability",	"endpoint":"ENM_0000068_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=ENM_0000068_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-321dc5bc-b61b-3a61-b9a3-6c733532782d/study?top=TOX",	"substance":"TiO2/SiO2 1:3",	"reference":"Calibrate D5.6",	"provider":"MISVIK",	"protocol":"CellTiter-Glo (CTG)",	"publicname":"T2 TIO2 / SIO2 1:3",	"substancetype":null,	"substance_uuid":"CLBR-321dc5bc-b61b-3a61-b9a3-6c733532782d",	"substance_owner":"caLIBRAte"	},
	{
	"value":"ENM_0000068. Cell Viability",	"endpoint":"ENM_0000068_SECTION",
	"count":2,
	"substancescount":-1,
	"uri":"https://apps.ideaconsult.net/calibrate/substance?type=endpointcategory&search=ENM_0000068_SECTION",
	"subcategory":"TOX",	"subcategoryuri":"https://apps.ideaconsult.net/calibrate/substance/CLBR-7e224a08-d7b1-3cb5-9bad-f55a649d1bd0/study?top=TOX",	"substance":"water",	"reference":"Calibrate D5.6",	"provider":"MISVIK",	"protocol":"CellTiter-Glo (CTG)",	"publicname":"WATER",	"substancetype":null,	"substance_uuid":"CLBR-7e224a08-d7b1-3cb5-9bad-f55a649d1bd0",	"substance_owner":"caLIBRAte"	}
]
}